sing TMS-EEG to assess effective connectivity

Completed

• Conditions: euroscientific research; N/A

• Registration Number: NL-OMON43761
• Lead Sponsor: Radboud Universiteit Nijmegen

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 23 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 96

Inclusion Criteria

Only healthy, competent, participants, 18*45 years old, with normal vision or corrected-to normal vision by means of contact lenses.

Exclusion Criteria

- Serious head trauma or brain surgery
- Previous history of epilepsy
- Large or ferromagnetic metal parts in the head (except for a dental wire)
- Implanted cardiac pacemaker or neurostimulator
- Pregnancy
- Large of ferromagnetic metal parts in the body
- Claustrophobia
- Skin diseases at intended electrode sites
- Disorders of vision (i.e., deviation from *normal or corrected-to-normal vision*)
- History or current presence of any neurologic or psychiatric disease
- Any prescribed medication that can alter cortical excitability (e.g. antiepileptics, tricyclic anti-depressives or benzodiazepines) or can have an influence on the participant*s vigilance or cognitive performance within two weeks prior to participation.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The amplitude of the TMS-evoked potential (TEP) in the EEG as a function of (1)<br /><br>stimulation area, (2) the presence or absence of an earlier pulse over<br /><br>connected brain areas, and (3) cognitive condition.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>N/A</p><br>