Comparison of effect and side effects of single dose and multiple dose methotrexate in treatment of tubal pregnancy and fertility 1 year after treatment
Phase 2
- Conditions
- Treatment of unruptured tubal pregnancy.Treatment of unruptured ectopic pregnancyO00, O01,O
- Registration Number
- IRCT201112178435N1
- Lead Sponsor
- Vice chancellor for research, Shahid Sadughi University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Female
- Target Recruitment
- 70
Inclusion Criteria
Inclusion criteria
gestational age less than 20 weeks; absence of bleeding in evidences of laparoscopic surgery and vaginal sonography; stable hemodynamic state; tubal mass equal or less than 4 cm in diameter; absence of fetal heart beat; ß -hCG less than 15000 mlU/mL, and leaning of patient to next pregnancy.
Exclusion criteria
Creatinine levels more than 1.5 mg/kg, Platelet levels more than 100000/ml, W.B.C levels more than 2000/ml, Higher than 2 times increased liver enzyme levels
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Success rates of treatment. Timepoint: Interval 48 hrs. on days 1,3,5,7. Method of measurement: Measurement of ß - hCG level.
- Secondary Outcome Measures
Name Time Method Fertility. Timepoint: 12 months after treatment. Method of measurement: Question about fertility.