Therapeutic effects of methotrexate in generalized lichen planus
Not Applicable
- Conditions
- ichen Planus.Subacute (active) lichen planus Lichen planus tropicus
- Registration Number
- IRCT201108187287N1
- Lead Sponsor
- Skin Research Center, Shohada-e-TajrishHospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 20
Inclusion Criteria
pathologically confirmed lichen planus and age between 18-75. Exclusion criteria: age less than 18 or more than 80 years old; pregnancy and lactation; chronic liver or kidney disease; use of systemic corticosteroids in last 6 month or application of topical steroids in last month and inability to come for follow up visits.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Rate of improvement. Timepoint: weeks 2, 4, 8 and 6 month after treatment. Method of measurement: Questionare and photograghy.
- Secondary Outcome Measures
Name Time Method iver dysfunction. Timepoint: baseline, 2 and 4 weeks after treatment. Method of measurement: Liver function test.;Bone marrow suppresion. Timepoint: Baseline, 1, 2 and 4 weeks after treatment. Method of measurement: Complete Blood Count.