omparison effect of single dose of Methotrexate and Actinomycin D in the prevention of gestational trophoblastic neoplasia in patients with high risk hydatidiform mole
Phase 3
- Conditions
- gestational trophoblastic neoplasmgestational trophoblastic neoplasia.O01.9
- Registration Number
- IRCT20130311012782N40
- Lead Sponsor
- Esfahan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Female
- Target Recruitment
- 90
Inclusion Criteria
Full molar pregnancy
mother age above 40 years old
Patient's consent to participate in the study
Patient Preparation for Surgery and Termination of Pregnancy with Suction for Molar Discharge
Having risk factors for pregnancy progression to trophoblastic neoplasia
Exclusion Criteria
serum level of B-hCG >=100000 iu/ml
theca lutein cyst size >=6 cm
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Incidence of gestational trophoblastic neoplasia in Molar pregnancy. Timepoint: Every week for three weeks and the 6 months later. Method of measurement: measurement of beta HCH.
- Secondary Outcome Measures
Name Time Method