Is it Possible to Replace Fentanyl in Anesthesia for Minor Procedures?

Not Applicable

Completed

• Conditions: Anesthesia
• Interventions: Drug: Ketamine; Drug: Fentanyl; Drug: Propofol; Drug: Cisatracurium; Drug: Lidocaine

• Registration Number: NCT03806374
• Lead Sponsor: Ain Shams University

Brief Summary

To compare between fentanyl group and ketamine lidocaine group for induction of anesthesia as regards hemodynamics and smooth intubation.

Detailed Description

Two groups each with 60 patients Group I anesthesia initiated by propofol, fentanyl and cisatracurium. Group II anesthesia initiated by ketamine, lidocaine, propofol and cisatracurium.

Study Timeline

• Study Start: 2018-01-02
• Primary Completion: 2018-12-01
• Study Completion: 2018-12-10
• Study First Submitted: 2018-12-11
• Status Verified: 2019-01
• Study First Submitted QC: 2019-01-15
• Last Update Submitted: 2019-01-15
• Study First Posted: 2019-01-16
• Last Update Posted: 2019-01-16

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 120

Inclusion Criteria

• ASA I and II between
• Age between 18-55 years
• Undergoing minor surgical procedure less than an hour.

Exclusion Criteria

• Patients with hypertension
• Patients with Ischemic heart diseases
• Patients with chronic renal or liver diseases

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Fentanyl	Fentanyl	Administered propofol and fentanyl for induction.
Fentanyl	Cisatracurium	Administered propofol and fentanyl for induction.
Ketamine and lidocaine	Propofol	Administered propofol, ketamine and lidocaine for induction.
Ketamine and lidocaine	Cisatracurium	Administered propofol, ketamine and lidocaine for induction.
Ketamine and lidocaine	Lidocaine	Administered propofol, ketamine and lidocaine for induction.
Fentanyl	Propofol	Administered propofol and fentanyl for induction.
Ketamine and lidocaine	Ketamine	Administered propofol, ketamine and lidocaine for induction.

Primary Outcome Measures

Name	Time	Method
Intubation with less hemodynamic changes	Anesthesia time	changes in pulse rate during anesthesia
Smooth Maintenance of anesthesia	anesthesia time	changes in blood pressure during anesthesia
less postoperative pain killers	24 hours postoperative	amount of pain killers used and timing

Trial Locations

Locations (1)

Ain Shams University hospitals; 🇪🇬 Cairo, Egypt