Effect of intraoperative dexmedetomidine intravenous infusion on postoperative morphine consumption after open thoracotomy

Phase 2

Recruiting

• Conditions: Open thoracotomy; open thoracotomy; Dexmedetomidine; Morphine consumption

• Registration Number: TCTR20210226003
• Lead Sponsor: Faculty of Medicine, Khon Kaen University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2021-02-26
• Study Completion: 2022-07-09
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

1. patient undergo open thoracotomy
2. Age 18-65 year
3. ASA physical status I-III

Exclusion Criteria

previous ipsilateral opern thoracotomy
Dexmedetomidine allergy
chronic pain
opioid addiction
Ejection fraction (EF) less than 35
more than first degree AV block
GFR less than 30
Liver failure
Alter mental status
cannot accept or deny research
pyschiatric disorder
pregnancy
breast feeding

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Morphine consumption 24 hr PCA

Secondary Outcome Measures

Name	Time	Method
pain score at rest and movement 2, 6, 12, 24 hr after end of operation numeric rating scale,side effect of dexmedetomidine and morphine 2, 6, 12, 24 hr after end of operation