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The effect of naltrexone in lichen planopilaris

Phase 2
Recruiting
Conditions
ichen Planopilaris.
Lichen planopilaris
Registration Number
IRCT20180809040747N1
Lead Sponsor
Tehran University of Medical Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
All
Target Recruitment
34
Inclusion Criteria

Diagnosis of Lichenplanopilaris (LPP) based on pathology

Exclusion Criteria

Burn-out lesions
Any treatments for lichenplanopilaris within the last month
History of drug addiction or alcohol abuse
History of psychiatric disorders
Willing to get or being pregnant
Consumption of drugs interfering with naltrexone (e.g. opioid antagonists)
Generalized cutaneous or mucosal lichen plan

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
ichen Planopilaris Acivity Index (LPPAI) Score. Timepoint: before intervention and 2, 4 , 6 months after intervention. Method of measurement: LPPAI Questionnair.
Secondary Outcome Measures
NameTimeMethod
Treatment tolerance. Timepoint: 2, 4 and 6 months after intervention. Method of measurement: Interview.;ESR. Timepoint: Before intervention and 2, 4 and 6 months after intervention. Method of measurement: Lab kit.
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