跳至主要内容
临床试验/NCT07096752
NCT07096752尚未招募不适用

Screening and Validation of Serum Protein Biomarkers for Early Diagnosis of Gastric Cancer

Shanghai Zhongshan Hospital0 个研究点目标入组 1,200 人开始时间: 2025年8月1日最近更新:

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
1,200
主要终点
Diagnostic Performance of the Serum Protein Biomarker-Based Model for Gastric Cancer

研究概览

简要总结

This study focuses on the discovery of protein biomarkers for the early diagnosis of gastric cancer and the development of corresponding detection methods. By employing advanced mass spectrometry-based proteomic technologies, the investigators conducted an in-depth analysis of a large cohort of clinical samples to identify specific protein biomarkers capable of accurately distinguishing gastric cancer patients from healthy individuals. The findings from this research are expected to facilitate the development of novel non-invasive or minimally invasive diagnostic approaches, thereby improving early detection, enhancing patient prognosis, and increasing survival rates.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
18 Years 至 95 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • 未提供

排除标准

  • 未提供

结局指标

主要结局

Diagnostic Performance of the Serum Protein Biomarker-Based Model for Gastric Cancer

时间窗: 3 years

Evaluation of the sensitivity and specificity of a diagnostic model constructed using key serum protein biomarkers for the early detection of gastric cancer.

次要结局

  • Predictive performance of the serum protein model for response to neoadjuvant therapy in gastric cancer(3 years)
  • Predictive performance of the serum protein model for the progression risk from precancerous gastric lesions to gastric cancer(3 years)
  • Prognostic performance of the serum protein model in gastric cancer patients(3 years)

研究者

发起方
Shanghai Zhongshan Hospital
申办方类型
Other
责任方
Principal Investigator
主要研究者

Hao-Jie Li

Doctor

Shanghai Zhongshan Hospital

相似试验