Screening and Validation of Serum Protein Biomarkers for Early Diagnosis of Gastric Cancer
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 1,200
- 主要终点
- Diagnostic Performance of the Serum Protein Biomarker-Based Model for Gastric Cancer
研究概览
简要总结
This study focuses on the discovery of protein biomarkers for the early diagnosis of gastric cancer and the development of corresponding detection methods. By employing advanced mass spectrometry-based proteomic technologies, the investigators conducted an in-depth analysis of a large cohort of clinical samples to identify specific protein biomarkers capable of accurately distinguishing gastric cancer patients from healthy individuals. The findings from this research are expected to facilitate the development of novel non-invasive or minimally invasive diagnostic approaches, thereby improving early detection, enhancing patient prognosis, and increasing survival rates.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 95 Years(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- 未提供
排除标准
- 未提供
结局指标
主要结局
Diagnostic Performance of the Serum Protein Biomarker-Based Model for Gastric Cancer
时间窗: 3 years
Evaluation of the sensitivity and specificity of a diagnostic model constructed using key serum protein biomarkers for the early detection of gastric cancer.
次要结局
- Predictive performance of the serum protein model for response to neoadjuvant therapy in gastric cancer(3 years)
- Predictive performance of the serum protein model for the progression risk from precancerous gastric lesions to gastric cancer(3 years)
- Prognostic performance of the serum protein model in gastric cancer patients(3 years)
研究者
Hao-Jie Li
Doctor
Shanghai Zhongshan Hospital
