The ED-CO study: screening for carbon monoxide exposure in the emergency department
- Conditions
- Carbon monoxide poisoningInjury, Occupational Diseases, PoisoningAccidental poisoning by and exposure to other gases and vapours
- Registration Number
- ISRCTN16329899
- Lead Sponsor
- St George's University Hospitals NHS Foundation Trust
- Brief Summary
2023 Results article in https://doi.org/10.1093/pubmed/fdad007 (added 03/01/2024)
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 4404
1. Aged 18 years or older
2. Presenting to the ED with symptoms suggestive of cardiac chest pain, non-traumatic headache, flu-like symptoms unless suggestive of specific focus of infection, seizures or syncope/presyncope
1. Aged under 18 years
2. Chest pain associated with chest wall tenderness or non-cardiac cause (pulmonary embolism, pneumothorax)
3. Recurrent situational syncope
4. Head injury
5. Actual or suspected smoke inhalation
6. Unable to understand the informed consent process and/or has a poor understanding of English (e.g. English-speaking relative/translator not available within timescales for study procedures)
7. Patients previously enrolled in this study
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Carboxyhemoglobin (COHb) level in blood sample provided on day of presentation to Emergency Department
- Secondary Outcome Measures
Name Time Method <br> 1. Answers to questions in the COMA screening questionnaire provided by patient on day of presentation to Emergency Department<br> 2. Time of year of confirmed or suspected CO exposure (summer versus winter) assessed using patient medical records and gas engineer data following presentation<br> 3. Diagnosis of dementia during the 28 days following presentation assessed using patient medical records<br>