Registry of Patients With Hematologic Disease and COVID-19 in Russia
- Conditions
- Coronavirus Infection and Hematologic Diseases
- Registration Number
- NCT04422470
- Lead Sponsor
- National Research Center for Hematology, Russia
- Brief Summary
This is an observational prospective cohort study to evaluate the clinical course and outcomes of COVID-19 and the underlying disease in patients with hematologic disease (malignant or non-malignant).
- Detailed Description
This is a web-based registry. After registration, physicians from hematology clinical centers and hospitals in Russia will receive access to the web platform for clinical trial management to fill in the online data collection form in a de-identified manner. This form includes questions about general clinical history of hematologic disease, manifestation, treatment, and the course of COVID-19, concomitant conditions, consequences on the hematologic disease, short-term and long-term outcomes. It will take approximately 10 min to answer the questions. Patients will be followed for 30 days after COVID-19 diagnosis and up to 6 months for hematologic disease outcomes and overall survival assessment.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 666
Not provided
Not provided
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 30-day all-cause mortality 30 day Rate of death from any cause
- Secondary Outcome Measures
Name Time Method Relapse or progression of hematologic disease 30 day, 90 day and 180 day Rate of relapse or progression of hematologic disease
Overall survival 30 day, 90 day and 180 day Number of patients alive
ICU admission 30 day Rate of ICU admission
COVID-19 complications 30 day Rate of COVID-19 complications
Mechanical ventilation / O2 requirement 30 day Rate of mechanical ventilation / O2 requirement
Risk factors 30 day, 90 day and 180 day Putative risk factors for the severity and lethality of COVID-19
Trial Locations
- Locations (13)
National Research Center for Hematology
🇷🇺Moscow, Russian Federation
RM Gorbacheva Research Institute of Pediatric Oncology, Hematology and Transplantation, Pavlov University
🇷🇺Saint Petersburg, Russian Federation
Regional Clinical Hospital No1
🇷🇺Ekaterinburg, Russian Federation
Clinical Hospital n.a. S.P. Botkin
🇷🇺Moscow, Russian Federation
Regional Clinical Hospital No2
🇷🇺Vladivostok, Russian Federation
N.V. Sklifosovsky Emergency Institute
🇷🇺Moscow, Russian Federation
Republican Clinical Hospital of Tatarstan
🇷🇺Kazan, Russian Federation
Regional Hospital
🇷🇺Novosibirsk, Russian Federation
Republic Clinical Hospital n.a. N.A. Semashko
🇷🇺Ulan-Ude, Russian Federation
Republican Clinical Hospital No4
🇷🇺Saransk, Russian Federation
City Hospital n.a. V.V. Veresaev
🇷🇺Moscow, Russian Federation
Regional Clinical Hospital N.A. Semashko
🇷🇺Nizhny Novgorod, Russian Federation
Regional Clinical Hospital
🇷🇺Yaroslavl, Russian Federation