MedPath

AN2 Therapeutics

AN2 Therapeutics logo
🇺🇸United States
Ownership
Public
Established
2017-01-01
Employees
41
Market Cap
$34.9M
Website
http://www.an2therapeutics.com
Introduction

AN2 Therapeutics, Inc. operates as a global health biopharmaceutical company. The firm focuses on modern biomedical and drug development to provide transformational medicines for patients suffering from infectious diseases. The company was founded by Eric Easom, George Harrison Talbot, Joseph S. Zakrzewski and Michael R.K. Alley and is headquartered in Menlo Park, CA.

Clinical Trials

8

Active:0
Completed:5

Trial Phases

2 Phases

Phase 1:4
Phase 2:1

Drug Approvals

0

Drug Approvals

No drug approvals found

This company may not have drug approvals in our database

Clinical Trials

Distribution across different clinical trial phases (5 trials with phase data)• Click on a phase to view related trials

Phase 1
4 (80.0%)
Phase 2
1 (20.0%)

First-in-Human Trial of Oral AN2-502998

Phase 1
Recruiting
Conditions
Healthy Volunteers
Interventions
Drug: Placebo
First Posted Date
2025-06-17
Last Posted Date
2025-07-10
Lead Sponsor
AN2 Therapeutics, Inc
Target Recruit Count
64
Registration Number
NCT07024589
Locations
🇦🇺

Nucleus Network, Melbourne, Victoria, Australia

An Observational Study to Evaluate Clinical Characteristics of Adult Patients With Suspected or Confirmed Melioidosis

Completed
Conditions
Melioidosis
First Posted Date
2023-10-18
Last Posted Date
2025-05-31
Lead Sponsor
AN2 Therapeutics, Inc
Target Recruit Count
200
Registration Number
NCT06089668
Locations
🇱🇦

Mahosot Hospital, Vientiane, Lao People's Democratic Republic

🇹🇭

Srinagarind Hospital, Khon Kaen, Thailand

🇹🇭

Sunpasitthiprasong Hospital, Ubon Ratchathani, Thailand

A Study to Assess the Effects of Epetraborole on the QT Interval in Healthy Adult Subjects

Phase 1
Completed
Conditions
Healthy Volunteers
Interventions
First Posted Date
2023-08-16
Last Posted Date
2023-12-21
Lead Sponsor
AN2 Therapeutics, Inc
Target Recruit Count
24
Registration Number
NCT05995444
Locations
🇺🇸

423001, Tempe, Arizona, United States

Study of Epetraborole in Patients With Treatment-refractory MAC Lung Disease

Phase 2
Terminated
Conditions
MAC Lung Disease
Treatment Refractory MAC Lung Disease
Interventions
Drug: Placebo
First Posted Date
2022-04-14
Last Posted Date
2025-05-08
Lead Sponsor
AN2 Therapeutics, Inc
Target Recruit Count
177
Registration Number
NCT05327803
Locations
🇺🇸

423032, Birmingham, Alabama, United States

🇺🇸

423037, Tucson, Arizona, United States

🇺🇸

423070, Sacramento, California, United States

and more 88 locations

A Study of Epetraborole Tablets in Subjects With Degrees of Renal Function

Phase 1
Completed
Conditions
Renal Insufficiency
Interventions
First Posted Date
2022-03-17
Last Posted Date
2022-07-15
Lead Sponsor
AN2 Therapeutics, Inc
Target Recruit Count
40
Registration Number
NCT05283746
Locations
🇺🇸

Advanced Pharma CR, Miami, Florida, United States

🇺🇸

Orlando Clinical Research Center, Orlando, Florida, United States

🇺🇸

Nucleus Network, Saint Paul, Minnesota, United States

  • Prev
  • 1
  • 2
  • Next

News

AN2 Therapeutics Completes 200-Patient Study Revealing 40% Mortality Rate in Acute Melioidosis

AN2 Therapeutics completed a 200-patient observational study in acute melioidosis, revealing a striking mortality rate of nearly 40% by Day 90 despite standard of care treatment.

Aligos Therapeutics Strengthens CMC Leadership with Industry Veteran Ahead of Phase 2 Trial

Aligos Therapeutics has appointed Kieron Wesson, PhD as Vice President, Head of Chemistry Manufacturing Controls (CMC), bringing over 20 years of pharmaceutical development experience to the company.

AN2 Therapeutics Shifts Phase 3 MAC Lung Disease Trial to Quality of Life Endpoint

AN2 Therapeutics has selected Quality of Life-Bronchiectasis (QOL-B) respiratory domain as the new primary efficacy endpoint for their Phase 3 EBO-301 trial in treatment-refractory MAC lung disease.

AN2 Therapeutics' Epetraborole Shows Promise in Phase 2 NTM Lung Disease Trial

Phase 2 clinical trials of epetraborole demonstrated significant improvements in respiratory quality of life for patients with refractory MAC NTM lung disease, supporting advancement to Phase 3 studies.

© Copyright 2025. All Rights Reserved by MedPath