Ropivacaine Use in Interscalene Block; What is the Minimal Effective Analgesic Concentration (MEAC 90)
- Conditions
- Postoperative Pain
- Registration Number
- NCT04833296
- Lead Sponsor
- Healthpoint Hospital
- Brief Summary
This study aim to calculate the minimal effective ropivacaine concentration required achieve successful analgesic interscalene block in 90% of patients (MEAC90)
- Detailed Description
* Before induction of general anesthesia, all patients will receive interscalene block using 15ml of ropivacaine which concentration will be based on the response of the previous patient.
* Based on biased-coin design up-down sequential method: if patient has pain free recovery, a successful block, the next patient will be randomized to receive either the same ropivacaine concentration or a concentration 0.01% w/v less. However, if he has an unsuccessful block, the next patient will receive a concentration 0.01% w/v higher.
* Patients with pain free recovery will be considered to have positive response.
* Patients' responses will be analyzed to calculate the MEAC90.
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 45
- Patients, who are scheduled for shoulder arthroscopy
-
- <18 y,
-
ASA physical class greater >III
- BMI >40 has any contraindication for medications or techniques used in the study
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Primary Outcome Measures
Name Time Method effective analgesic interscalene block in recovery unit (one hour after surgery) postoperative pain (will be assessed using numerical rating scale. if ≥ 3, ineffective block will be considered and if \<3, an effective block will be considered
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Healthpoint Hospital
🇦🇪Abu Dhabi, United Arab Emirates