Impact of Zumba Exercise Training on Arterial Stiffness, Pulse Wave Velocity and Serum Homocysteine levels among female adults with Polycystic Ovarian Syndrome.
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 54
- 试验地点
- 1
- 主要终点
- 1. Decrease in arterial stiffness
研究概览
简要总结
This randomized controlled trial with aims to evaluate the impact of Zumba training on arterial stiffness, pulse wave velocity (PWV), and other health parameters in women aged 18–25 with PCOS by measuring parameters before and after 3 months of Zumba exercise. A total of 54 participants will be randomized into a Zumba intervention group and a control group receiving standard care. The intervention involves 168 minutes of Zumba weekly (24 minutes daily), online sessions over three months. Key outcomes include anthropometric measurements (e.g., BMI, waist-to-hip ratio), physiological parameters (e.g., heart rate, blood pressure, Pulse wave velocity, Augmentation Index, Resting heart rate variability ), psychophysiological factors (e.g., stress levels, sleep quality), and serum homocysteine levels.
This study has significant implications. Clinically, Zumba could serve as a non-pharmacological intervention to improve vascular health and reduce CVD risk in women with PCOS. From a public health perspective, integrating enjoyable exercise programs like Zumba into broader health initiatives could enhance adherence, reduce PCOS-related complications, and promote cardiovascular health across populations.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Outcome Assessor Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 25.00 Year(s)（—）
- 性别
- Female
入选标准
- •1.Modified Rotterdam criteria, in which PCOS may be diagnosed if any two of the following are present: (1) clinical or biochemical hyperandrogenism, (2) evidence of oligo-anovulation, (3) polycystic appearing-ovarian morphology on ultrasound, with exclusion of other relevant disorders.
- •2.Nonpregnant woman 3.Recently diagnosed PCOS participants 4.Willingness to participate in the study and provide informed consent.
排除标准
- •1.Participants who are on oral contraceptive pills (OCP) 2.History of chronic systemic illness (DM, HT, TB, etc) 3.Subjects currently on medication against systemic diseases 4.Smokers and Alcoholic 5.History of cardiovascular or cerebrovascular disease.
- •6.Pregnancy or planning pregnancy during the study period.
- •7.Use of medications that could affect vascular function (e.g., anticoagulants).
- •Women who did not consent.
结局指标
主要结局
1. Decrease in arterial stiffness
时间窗: 3 months
(measured by pulse wave velocity and augmentation index).
时间窗: 3 months
2. Decrease in serum homocysteine levels.
时间窗: 3 months
次要结局
- 1. Decrease in Blood Pressure(2. Change in Body Composition( measured by BMI, waist circumference, Waist to hip ratio))
研究者
Manisha R
All India Institute of Medical Sciences, Mangalagiri.