Effects of Breaking Sitting on Human Behaviour and Metabolic Health

Not Applicable

Completed

• Conditions: Physical Activity Level; Energy Balance; Cognition; Metabolic Health
• Interventions: Behavioral: Prolonged sitting; Behavioral: Breaking prolonged sitting

• Registration Number: NCT05911490
• Lead Sponsor: National Taiwan Normal University

Brief Summary

This study primarily aimed to investigate effects of breaking up prolonged sitting with intermittent brisk walking in healthy young individuals on (1) post-trial human behaviours including energy intake and physical activity under free-living conditions and (2) cognitive performance in a simulated workplace environment.

Detailed Description

Not available

Study Timeline

• Study Start: 2019-12-20
• Primary Completion: 2020-09-29
• Study Completion: 2020-09-29
• Study First Submitted: 2023-05-20
• Status Verified: 2023-06
• Study First Submitted QC: 2023-06-09
• Last Update Submitted: 2023-06-09
• Study First Posted: 2023-06-22
• Last Update Posted: 2023-06-22

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 24

Inclusion Criteria

• Without current and any history of brain injury, neurological disorder, cardiometabolic related diseases, diabetes or cancers.
• Weight stable (not self-reported weight change ± 3 kg at least 3 months)
• Body mass index (BMI) ranging between 18.5 to 27 kg/m2
• Can walk safely on a treadmill

Exclusion Criteria

• Smokers, post-menopausal female, and volunteers who used any medications that could influence metabolic and inflammatory responses.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
Prolonged sitting	Prolonged sitting	Participants sat on a chair during the trial in the laboratory.
Breaking prolonged sitting	Breaking prolonged sitting	Participants walked regularly during the trial in the laboratory.

Primary Outcome Measures

Name	Time	Method
Energy intake	480 minutes	Changes in energy intake (kcal) in the free-living conditions
Cognitive function	320 minutes	Changes in cognitive performance (% changes in reaction time) Task Switching and Flanker tasks
Physical activity level	480 minutes	Changes in physical activity level (steps) in the free-living conditions
Cognitive performance	320 minutes	Changes in cognitive performance (% changes in accuracy) including Task Switching and Flanker tasks

Secondary Outcome Measures

Name	Time	Method
Visual analogue scale (VAS)	320 minutes	Changes in self-perceived sensations including appetite, energy and mood (score from 0-100)
Postprandial glucose concentrations	320 minutes	Changes in postprandial finger pricking glucose concentrations
Blood pressure	320 minutes	Changes in systolic blood pressure and diastolic blood pressure
Continuous glucose monitoring	320 minutes	Changes in different depots of adipose tissue interstitial glucose concentrations

Trial Locations

Locations (1)

National Taiwan Normal University; 🇨🇳 Taipei, Taiwan