Analysis for changing the arterial-to-end-tidal CO2 difference under pneumoperitoneum (PP)
- Conditions
- aparoscopic operation
- Registration Number
- DRKS00006731
- Lead Sponsor
- Klinik für Anästesiologie und IntensivtherapieUniversitätsklinikum Magdeburg
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 18
1. Age: 18 - 75 years
2. Gender: male and female
3. race: caucasian
4. Body weight: BMI from 18
5. patients undergoing clinically indicated laparoscopic surgery
6. assent to necessary measures (arterial access or arterial puncture) with the written consent
1. reduced lung function (FEV1 / VC <70% and FEV1 <80%)
2. COPD, Z.n. Status asthmaticus
3. Third right-to-left shunt or left-to-right shunt
4. pneumonia, pulmonary edema or state after pulmonary embolism
5. interstitial lung diseases
6. large pleural effusions
7. heart failure (NYHA III and IV)
8. systolic blood pressure <100 mmHg and diastolic <50 mmHg, volume depletion
9. decompensated liver or kidney disease
10. infection within the last 14 days
11. Contraindications to arterial access or arterial puncture (eg Allen test)
12. Refusal to participate in the study by the patient
Study & Design
- Study Type
- observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The aim of this study is to investigate whether, after creating a pneumoperitoneum during laparoscopic surgery an increase in the arterial-to-end-tidal CO2 concentration was recorded<br>1. Determination of arterial CO2 content by arterial blood gas analysis at various time points<br>- After induction of anesthesia<br>- Before performing a recruitment maneuver (RM),<br>- After completion of the RM<br>- Before induction of PP,<br>- Immediately after induction of PP and<br>- During which time in 30 minute intervals<br>- Once after completion of the PP<br>
- Secondary Outcome Measures
Name Time Method Occur Study about the occurrence of differences in the range of the CO2 difference between patients with normal weight, overweight and obese