Comparison of the performance of two pain monitoring devices Analgesia Nociceptive Index ( derived from ECG) and Surgical Pleth Index ( derived from pluse oximetry) in the setting of sudden blood loss during surgery.
Not Applicable
- Conditions
- Health Condition 1: null- Patients with Traumatic brain injury ( Acute subdural hematoma, Extradural hematoma, contusions), meningioma undergoing surgery
- Registration Number
- CTRI/2018/05/014265
- Lead Sponsor
- ational Institute of Mental Health and Neurosciences NIMHANS
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1. Expected blood loss > 500 ml.
2. Highly vascular meningioma based on CT/ MRI/ DSA.
Exclusion Criteria
Patients with bilateral head injury (similar extent of injury on opposite side),
Patients with baseline heart rate > 100 bpm after intubation and fluid resuscitation,
Patients on treatment with beta blockers, clonidine,neostigmine, atropine, glycopyrrolate,
Patients with known drug allergy to local anaesthetics,
Pregnancy,
Patients with cardiac arrhythmias,
Duration of surgery < 1 hr,
Baseline Haemoglobin (Hb) < 8g/dl,
Patients refusing to give consent
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method