Benefits of Analgesia Nociception Index Guided Fentanyl administration in critically ill patient: A randomized controlled trial
Phase 2
- Conditions
- more than 18-year intubated patient in intensive care unit who required intravenous anesthetic drug and fentanyl.intubated patient, opioid consumption, pain assessment, analgesia Nociception Index, ANI, sedation in intensive care unit
- Registration Number
- TCTR20221031002
- Lead Sponsor
- /A
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- nknown
- Sex
- All
- Target Recruitment
- 50
Inclusion Criteria
1. More than 18-year intubated patient admitted to intensive care unit with.
2. Required intravenous anesthetic drug and fentanyl for sedate.
3. Accept to participate in the research project and sign a letter of consent to participate in the research project.
Exclusion Criteria
1. Patient with unstable hemodynamic requiring high dose of vasopressor
2. Patient with cardiac arrythmia
3. Patient with chronic opioid used
4. Patient with autonomic dysfunction
5. Patient with allergic to study drug
6. Patient refuse to participate in research projects or withdraw from research.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method fentanyl consumption at 48 h at 48 h after enrollment ANI
- Secondary Outcome Measures
Name Time Method Correlation of pain measurement at 4,8,12,16,20,24,28,32,36.40,44 and 48 h after enrolled ANI and BPS score,Association of side effects from the use of analgesics with the amount of analgesics used. ICU stayed CAM-ICU, withdrawal symptom