Comparison of Analgesia Nociception Index (ANI) guided analgesia administration with Standard Clinical Practice during Routine General Anaesthesia

Phase 1

Completed

• Conditions: Acute Pain; Anaesthesiology - Anaesthetics; Anaesthesiology - Pain management

• Registration Number: ACTRN12614000169640
• Lead Sponsor: The University of Adelaide

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2014-02-11
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

Patients scheduled for non-emergent, spinal surgery, aged 18-75 years, American Society of Anesthesiologists (ASA) score 1 or 2, competent to consent to participation, able to use a Visual Analogue Scale (VAS) and able to activate a patient controlled analgesia (PCA) machine post-operatively.

Exclusion Criteria

Emergency surgery
Inability to consent, lack of written consent or speak English fluently
Pregnancy or lactation. Pregnancy test will be performed in all women of child bearing potential
Cardiac morbidity
Non-regular sinus cardiac rhythym
Cardiac disease which impacts usual daily functioning (equivalent to ASA greater than or equal to 3)
Implanted cardiac pacemaker
Concurrent medications with a major effect affect upon the sinus node
Expected duration of surgery greater than 3 hours (180 minutes)
Extremes of weight (Body Mass Index less than or equal to 19 or greater than or equal to 35 kg per meter squared)
Pre-operative chronic opioid use or chronic pain, equivalent to oxycodone 20mg per oral, per day for more than 6 weeks
Allergy or intolerance to any of the study drugs
Use of neuraxial anaesthesia

Study & Design

• Study Type: Interventional
• Study Design: Not specified