A Clinical Study to Compare Two Different Methods of Using The Drug Tranexamic Acid To Reduce Bleeding In Patients Undergoing Cardiac Valve Replacement Surgeries
Not Applicable
Completed
- Conditions
- Health Condition 1: I359- Nonrheumatic aortic valve disorder, unspecifiedHealth Condition 2: I349- Nonrheumatic mitral valve disorder, unspecifiedHealth Condition 3: I369- Nonrheumatic tricuspid valve disorder, unspecifiedHealth Condition 4: I069- Rheumatic aortic valve disease, unspecifiedHealth Condition 5: I089- Rheumatic multiple valve disease,unspecified
- Registration Number
- CTRI/2019/09/021376
- Lead Sponsor
- SRM Medical College Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 80
Inclusion Criteria
1.Elective Surgeries
2.Cardiac Valve Replacement or Repair
3.ASA I-III
Exclusion Criteria
1.Emergency surgeries
2.Re-do surgeries
3.Renal Insufficiency(Creatinine >1.8)
4.Hepatic Insufficiency(Direct Bilirubin >2.0)
5.Pre-existing coagulopathy
6.Pre-existing Deep vein thrombosis/Pulmonary embolism
7.Patients on anticoagulant medications (within 5 days before surgery)
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To evaluate the amount of blood lossTimepoint: upto 48 hours
- Secondary Outcome Measures
Name Time Method Requirement of blood transfusions and incidence of side effectsTimepoint: Upto 5 days post-operatively