The evaluation of clinical effect of locally delivered minocycline hydrochloride in the surgical treatment of peri-implantitis: a randomized clinical trial

Yonsei University Health System, Dental Hospital0 个研究点目标入组 48 人开始时间: 待定最近更新: 2019年3月11日

适应症

试验速览

暂无简介。

•The following inclusion criteria were applied:
•-Diagnostic criteria of peri-implantitis; peri-implant bone loss > 2mm, probing depth > 5mm, bleeding on probing/suppuration and presence of plaque (Lang et al. 2004)
•-No history of active (surgical) treatment for peri-implantitis
•-Bone loss that occurred apical to the reference point established based on implant system when there is no radiographic data that can be used as the baseline
•The reference points according to the implant system are as follows:
•Branemark type: First thread
•Straumann type: 2.8mm(standard) / 1.8mm(standard plus) below the implant shoulder
•Astra tech type: 1.8mm below the implant shoulder
•Reference) Effectiveness of Implant Therapy Analyzed in a Swedish Population: Prevalence of Peri-implantitis. Derks J, Schaller D, Håkansson J, Wennström JL, Tomasi C, Berglundh T.J Dent Res. 2016 Jan;95(1):43-9.

•The following exclusion criteria were applied:
•-Presence of pregnancy or lactation.
•-Taking drugs that can affect periodontal disease (phenytoin, cyclosporine, and calcium channel blockers).
•-Taking Coumadin or non-steroidal anti-inflammatory drugs.
•-Presence of diabetes mellitus, smoking (except former smoking with cessation at least 10
•-Those who is allergies with tetracycline.
•-Those using chlorhexidine or any other mouth rinse.
•-Those who have taken antibiotics within the previous 3 months.

发起方

Yonsei University Health System, Dental Hospital