KCT0002844
Recruiting
未知
The evaluation of clinical effect of locally delivered minocycline hydrochloride in the surgical treatment of peri-implantitis: a randomized clinical trial
Yonsei University Health System, Dental Hospital0 sites48 target enrollmentTBD
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- Certain infectious and parasitic diseases
- Sponsor
- Yonsei University Health System, Dental Hospital
- Enrollment
- 48
- Status
- Recruiting
- Last Updated
- 7 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •The following inclusion criteria were applied:
- •\-Diagnostic criteria of peri\-implantitis; peri\-implant bone loss \> 2mm, probing depth \> 5mm, bleeding on probing/suppuration and presence of plaque (Lang et al. 2004\)
- •\-No history of active (surgical) treatment for peri\-implantitis
- •\-Bone loss that occurred apical to the reference point established based on implant system when there is no radiographic data that can be used as the baseline
- •The reference points according to the implant system are as follows:
- •Branemark type: First thread
- •Straumann type: 2\.8mm(standard) / 1\.8mm(standard plus) below the implant shoulder
- •Astra tech type: 1\.8mm below the implant shoulder
- •Reference) Effectiveness of Implant Therapy Analyzed in a Swedish Population: Prevalence of Peri\-implantitis. Derks J, Schaller D, Håkansson J, Wennström JL, Tomasi C, Berglundh T.J Dent Res. 2016 Jan;95(1\):43\-9\.
Exclusion Criteria
- •The following exclusion criteria were applied:
- •\-Presence of pregnancy or lactation.
- •\-Taking drugs that can affect periodontal disease (phenytoin, cyclosporine, and calcium channel blockers).
- •\-Taking Coumadin or non\-steroidal anti\-inflammatory drugs.
- •\-Presence of diabetes mellitus, smoking (except former smoking with cessation at least 10
- •\-Those who is allergies with tetracycline.
- •\-Those using chlorhexidine or any other mouth rinse.
- •\-Those who have taken antibiotics within the previous 3 months.
Outcomes
Primary Outcomes
Not specified
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