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Clinical Trials/NCT05938153
NCT05938153
Completed
Not Applicable

Evaluation of Metabolic Syndrome, Frailty, Locomotive Syndrome, Balance and Physical Fitness in Elderly Individuals

Kırıkkale University1 site in 1 country41 target enrollmentJune 1, 2023

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Geriatrics
Sponsor
Kırıkkale University
Enrollment
41
Locations
1
Primary Endpoint
Geriatric Locomotive Function Scale:
Status
Completed
Last Updated
4 months ago

Overview

Brief Summary

Metabolic syndrome (MetS) or syndrome X, which is increasingly prevalent in the world and in our country, is a disease that includes abdominal obesity, dyslipidemia, impaired glycemic control and hypertension components. It causes cardiovascular events such as myocardial hypertrophy, left ventricular diastolic dysfunction, atrial dilatation and atrial fibrillation. Low levels of physical activity can be caused by a wide variety of factors including environmental and genetic factors, age, race, sarcopenia, poor eating habits, postmenopausal period and smoking history. Factors such as genetic differences, diet, physical activity, age, gender and eating habits are reported to affect the prevalence of (MetS) and its components. Frailty is also emerging as a major issue for the elderly due to its debilitating effects on health outcomes. Frailty is a geriatric syndrome characterized by a gradual decrease in homeostatic tolerance and physiological reserve following exposure to stressors. Frailty predisposes older people to falls, delirium, hospitalizations and even death and is therefore considered a crucial transition between healthy ageing and disability. As a result of aging, degenerative changes in the central and peripheral vestibular system have been found. With age, the ability to regulate movement is impaired as a result of insufficient information in any of the sensory receptors or any disorder affecting the processing of these messages. This directly affects balance and postural control, leading to an increased risk of falls. In the light of the results of the studies in the literature, degenerative changes are observed in many systems in geriatric individuals and while the incidence of metabolic syndrome in these individuals is high, the number of studies evaluating their effects is not sufficient. Based on these deficiencies, it is aimed to examine metabolic syndrome, frailty, locomotive syndrome, balance and physical fitness in elderly individuals.

Registry
clinicaltrials.gov
Start Date
June 1, 2023
End Date
January 20, 2025
Last Updated
4 months ago
Study Type
Observational
Sex
All

Investigators

Sponsor
Kırıkkale University
Responsible Party
Principal Investigator
Principal Investigator

Alper Kemal Gürbüz

research asistant

Kırıkkale University

Eligibility Criteria

Inclusion Criteria

  • Individuals aged 65 and over,
  • Volunteering to participate in the research
  • No cooperation and communication problems

Exclusion Criteria

  • Individuals with neurological and orthopedic problems
  • Uncontrolled hypertension
  • Those with cardiac disorders
  • Those with cooperation and communication problems

Outcomes

Primary Outcomes

Geriatric Locomotive Function Scale:

Time Frame: 10 minute

This scale consists of a questionnaire of 25 items that can be easily understood by the elderly and each item is graded between 0 and 4 points. The total score is the result of the sum of all items ranging from 0 to 100; the higher the score, the higher the physical impairment of the elderly, with a score of 16 being the cut-off point for locomotive syndrome. The GLFS-25 includes 4 questions about pain, 16 questions about activities of daily living, 3 questions about social performance and 2 questions about mental health status to assess geriatric individuals. Turkish validity and reliability of the questionnaire was conducted by Sadikoglu.

Secondary Outcomes

  • Weight lifting test(2 minute)
  • Chair sit-lie test(5 minute)
  • Two-minute step test(2 minute)

Study Sites (1)

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