Clinical Evaluation of Injectable Platelet Rich Fibrin With Connective Tissue Graft for the Treatment of Deep Gingival Recession Defects. A Controlled Randomized Clinical Trial.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 72
- 试验地点
- 2
- 主要终点
- Keratized tissue height
研究概览
简要总结
Aim: The aim of this study was to determine whether the combined connective tissue graft (CTG) with injectable platelet rich fibrin (i-prf) with coronally advanced flap (CAF) improved root coverage of deep Miller Class I or II gingival recessions compared to CTG alone with CAF.
Methods: Seventy-two patients with Miller class I and II gingival recessions were enrolled. Thirty-six patients were randomly assigned to the test group (CAF+CTG+i-prf) or control group (CAF+CTG). Clinical evaluations were made at 6 months
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Triple (Participant, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •≥19 years of age,
- •Periodontally and systemically healthy,
- •FMPS and FMBS <15%,
- •Presence of deep Miller class I and II gingival recession defect (≥3 mm in depth) at the buccal aspect of incisors,
排除标准
- •Contraindications for surgery,
- •Presence of recession defects associated with caries, deep abrasion, restoration or pulpal pathology.
研究组 & 干预措施
CAF+CTG
the combined connective tissue graft (CTG) with coronally advanced flap (CAF)
干预措施: CAF+CTG+i-prf (Procedure)
CAF+CTG+i-prf
the combined connective tissue graft (CTG) and injectable platelet rich fibrin (i-prf) with coronally advanced flap (CAF)
干预措施: CAF+CTG+i-prf (Procedure)
结局指标
主要结局
Keratized tissue height
时间窗: six months
measured from the mucogingival junction to the gingival margin-measurements were performed at the midbuccal aspect of the teeth, by manual probe and were rounded up to the nearest millimetre
gingival recession depth
时间窗: six months
the distance between the CEJ and gingival margin-measurements were performed at the midbuccal aspect of the teeth, by manual probe and were rounded up to the nearest millimetre
次要结局
未报告次要终点
研究者
Mustafa Ozcan
Assistant Professor
Cukurova University