Effect of general anaesthesia versus brachial plexus block on neutrophil count, neutrophil to lymphocyte ratio, and platelet to lymphocyte ratio in patients undergoing upper limb fracture surgery
Phase 3
- Registration Number
- CTRI/2024/03/064439
- Lead Sponsor
- ttar Pradesh university of medical sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1). Body mass index 18.5- 24.9 kg/m2
2). American society of anaesthesiologists (ASA) physical status I and II
5). Patients scheduled for upper limb fracture surgeries
Exclusion Criteria
1). Patients/attendant refusal
2). Patient having an infection at the surgical site
3). Patient on chronic treatment with steroid or immunosuppressants
4). Patient on recent chemotherapy
5). Patient hepatic and renal dysfunction
6). Surgery duration >180 minutes
7). Patient converted to general anaesthesia due to brachial plexus block failure
8). Patients with pre operative abnormal leukocytes count, neutrophil count, lymphocyte count and platelet count
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Effect of general anaesthesia versus brachial plexus block on neutrophil to lymphocyte ratio <br/ ><br>Effect of general anaesthesia versus brachial plexus block on neutrophil count <br/ ><br>Effect of general anaesthesia versus brachial plexus block on platelet to lymphocyte ratioTimepoint: Pre op <br/ ><br>Just after surgery <br/ ><br>4 hour after surgery <br/ ><br>24 hour after surgery
- Secondary Outcome Measures
Name Time Method Effect of general anaesthesia versus brachial plexus block on neutrophil countTimepoint: Pre op <br/ ><br>Just after surgery <br/ ><br>4 hour after surgery <br/ ><br>24 hour after surgery;Effect of general anaesthesia versus brachial plexus block on platelet to lymphocyte ratioTimepoint: Pre op <br/ ><br>Just after surgery <br/ ><br>4 hour after surgery <br/ ><br>24 hour after surgery