Function and Morphological Characteristics of Meibomian Gland in Patients With Renal Anemia
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- Lacrimal river height
研究概览
简要总结
Renal anemia refers to anemia in which the absolute or relative production of erythropoietin (EPO) is insufficient due to various kidney diseases, and uremic toxins affect erythropoietin production and its lifespan. Common treatment drugs for renal anemia include erythropoietin EPO and Roxadustat (FG-4592).
Medical history information was collected from patients with renal anemia who visited the ophthalmology department with dry eye symptoms.
This study will help to determine the function and morphological characteristics of meibomian gland in patients with renal anemia
详细描述
- Collect medical records of patients with renal anemia who visited the ophthalmology outpatient department of Zhongnan Hospital and hospitalized patients with renal anemia
- Patients were divided into Rosallistat group, and EPO group according to their drug use history.
- The dry eye analysis results of all patients were collected, and the lacrimal river height, tear film rupture time and meibomian gland grade were counted. The results of dry eye examination were analyzed statistically.
- Complete data collection, conduct statistical analysis, and evaluate the analysis results.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Other
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •long-term use of Roxadustat or erythropoietin for renal anemia
排除标准
- •contact lens wearer, history of eye surgeries, systemic health conditions affecting ocular health and those who were unable to cooperate with examinations
研究组 & 干预措施
Roxadustat
Subjects were treated with Roxadustat for renal anemia
干预措施: Dry eye examination (Diagnostic Test)
EPO
Subjects were treated with EPO for renal anemia
干预措施: Dry eye examination (Diagnostic Test)
结局指标
主要结局
Lacrimal river height
时间窗: Immediately and six months later
Measured by dry eye analyzer machine
tear break-up time
时间窗: Immediately and six months later
Measured by dry eye analyzer machine
meibomian glands two-dimensional digital infrared images
时间窗: Immediately and six months later
Measured by dry eye analyzer
tear-film lipid layer thickness
时间窗: Immediately and six months later
Measured by dry eye analyzer machine
次要结局
未报告次要终点