Study on the mechanism of scalp acupuncture combined with brain-computer interface to promote the recovery of motor function after stroke
- Conditions
- stroke
- Registration Number
- ITMCTR2000003516
- Lead Sponsor
- Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of TCM
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- Not specified
1. Meet the diagnostic criteria for stroke, and be confirmed by CT or MRI;
2. Aged 30-75 years, regardless of gender;
3. The course of disease after stroke >= 1 month and <= 12 months;
4. Unilateral limb motor function decreased significantly (Fugl-Meyer <85);
5. Clear consciousness, National Institutes of Health Stroke Scale (NIHSS) score >= 6 (moderate stroke severity and above);
6. No cognitive dysfunction;
7. Understand and agree to participate in this study and sign an informed consent form.
1. Significant cognitive deficits (MMSE<16 points);
2. Other diseases or factors affecting limb activity, such as: fracture, severe arthritis, amputation, etc.;
3. After stroke, patients with complex regional pain syndrome have significant pain and swelling;
4. There are contraindications for magnetic resonance (such as: pacemakers, heart stents, artificial heart valves, fixed steel plates after fracture surgery, etc.);
5. Combining severe heart, liver, kidney, blood system diseases or infectious diseases;
6. Women who are pregnant or breastfeeding;
7. Have participated in other studies or are participating in other clinical studies 6 months before enrollment.
Study & Design
- Study Type
- Interventional study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Fugl-Meyer exercise assessment;
- Secondary Outcome Measures
Name Time Method Brunnstrom assessment;Mini-Mental State Examination, MMSE;Self-Rating Anxiety Scale, SAS;Trail Making Test A, TMTA;Kinesthetic and visual imagery questionnaire;Functional magnetic resonance imaging, fMRI;Modified Barthel index, MBI;Self-rating depression scale, SDS;Electroencephalogram, EEG;Action Research Arm Test;