Skip to main content
MedPathMedPath Home
Clinical Trials/IRCT20130523013442N23
IRCT20130523013442N23
Recruiting
未知

Efficacy of intra-articular injection of a newly developed plasma rich in growth factors (PRGF) versus hyaluronic acid on pain and function of patients with knee osteoarthritis: A single-blinded randomized clinical trial

Vice chancellor for research, Shahid Beheshti University of Medical Sciences0 sites60 target enrollmentTBD
Share to TwitterShare to FacebookShare to LinkedInShare to Reddit

Overview

Phase
未知
Intervention
Not specified
Conditions
Not specified
Sponsor
Vice chancellor for research, Shahid Beheshti University of Medical Sciences
Enrollment
60
Status
Recruiting
Last Updated
8 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSimilar Trials

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
TBD
End Date
TBD
Last Updated
8 years ago
Study Type
Interventional
Sex
All

Investigators

Sponsor
Vice chancellor for research, Shahid Beheshti University of Medical Sciences

Eligibility Criteria

Inclusion Criteria

  • •Age between 45\-75 years
  • •Symptomatic knee OA with the pain aggravated by weight bearing
  • •Symptoms lasting for at least 6 months despite conservative treatment
  • •Kellgren\-Lawrance radiology scoring system scores ranging from 2\-3

Exclusion Criteria

  • •History of trauma , surgery or any invasive procedure in the affected joint during the past 6 months
  • •Mal\-alignment in lower limbs and abnormal blood count or impared coagulation test
  • •Pregnant women
  • •Patients who were under immunosuppressant treatments
  • •Those with an underlying systemic arthropathy (secondary OA)
  • •Patients been treated with angiotensin converting enzyme inhibitors (ACE I) and significant deficiency in glucose 6 \- phosphate dehydrogenase (G6PD) level

Outcomes

Primary Outcomes

Not specified

Similar Trials

Active, not recruiting
Not Applicable
effectiveness of autologous platelet rich plasma intra articular injection in knee paiHealth Condition 1: M170- Bilateral primary osteoarthritis of knee
CTRI/2022/05/042778ICMR PG THESIS GRANT
Recruiting
Phase 2
The effectiveness of Hyaluronic acid/Chondroitin injection on knee performance after surgical fixation.
IRCT20170608034390N13Shahid Beheshti University of Medical Sciences32
Completed
Not Applicable
Short-term efficacy of intra-articular injection, PRP(platelet rich plasma) compared with placebo in patients with osteoarthritis of the kneeknee osteoarthritis.osteoarthritis(M15-M19)
IRCT2016030626922N1Zanjan university of medical sciences30
Not yet recruiting
Phase 2
Injection of blood cell components in knee joint for joint pain patients
CTRI/2024/05/068055Gandhi medical college
Completed
Not Applicable
The efficacy and safety of intra-articular injections with the tumour-necrotising factor alpha (TNFa) antagonist infliximab in patients with chronic or recurrent arthritis of the kneeArthritis, spondyloarthropathy, rheumatoid arthritisMusculoskeletal DiseasesOther rheumatoid arthritis
ISRCTN17726268eiden University Medical Centre (LUMC) (The Netherlands)40