Short-term efficacy of intra-articular injection, PRP(platelet rich plasma) compared with placebo in patients with osteoarthritis of the knee
- Conditions
- knee osteoarthritis.osteoarthritis(M15-M19)
- Registration Number
- IRCT2016030626922N1
- Lead Sponsor
- Zanjan university of medical sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 30
This study will be conducted in Vali-Asr Hospital Rheumatology Clinic of men and women in the age range 30-70 years with osteoarthritis of the America College of Rheumatology classification criteria (ACR) shall be verified and if both diseases with a severely infected knee and the severity of patients in radiology 3-2 (moderately severe) will be examined. There is pain in patients with osteoarthritis of the knees and feel Krypytasyvn detailed mechanical examinations and x-rays are symptoms. Exclusion criteria included osteoarthritis secondary to inflammatory diseases - osteoarthritis generalized - osteoarthritis with grade 1 and 4 - metabolic bone - back pain - patients during the last 3 months any intra-articular injection have or arthroscopy during the past year have had. Any severe deformity of the knee - the knee varus and valgus knee more than 5 degrees more than 5 degrees - associated diseases such as septic knee - tumor - Crystal arthropathy or stiff joint effusion - anticoagulant treatment of patients with Hb less than 10 - dysfunction platelets or blood platelet count less than 150,000 liters in Mbkrv is also pregnancy- older than 70 years of sustainable use of NSAIDS in the past 48 hours, systemic disease, such as ischemic heart disease - diabetes and hepatitis
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The severity of joint pain. Timepoint: 4-6week. Method of measurement: Patient interview questionnaire WOMAC + VAS.;The severity of stiffness. Timepoint: 4-6 week. Method of measurement: Patient interview questionnaire WOMAC + VAS.;Severity of joint dysfunction. Timepoint: 4-6 week. Method of measurement: Patient interview questionnaire WOMAC + VAS.
- Secondary Outcome Measures
Name Time Method