Assessing the Efficacy of Intra-articular Injection of High Molecular Weight Hyaluronic Acid on Knee Function of Patients with Tibial Plateau Fracture after Surgical Fixatio

Phase 2

• Conditions: Tibial Plateau Fracture.; Fracture of upper end of tibia; S82.1

• Registration Number: IRCT20170608034390N3
• Lead Sponsor: Shahid Beheshti University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 26 August 2019

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 32

Inclusion Criteria

Adults (18-65 years)
Tibial Plateau Fracture
Signing the Informed Consent

Exclusion Criteria

Pregnancy & Lactation
Diabetes Mellitus
Severe osteoarthritis
Sever Osteoporesis
Non-surgical patients (Active septic disorders of knee joint and tissues around the knee, Coagulopathies, Active rheumatologic disorders, Heart Failure, COPD, ....)
Open fractures
Failure to perform internal fixation due to extensive tissue damage

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Pain by Visual Analogue Scale (VAS) score. Timepoint: Starting point, 2 and 22 weeks after first Injection. Method of measurement: Using standard scale for VAS score.

Secondary Outcome Measures

Name	Time	Method
Range of Motion. Timepoint: Starting point (2 weeks after fixation operation), 2 and 22 weeks after first Injection. Method of measurement: Using goniometer.;Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC Score). Timepoint: Starting point, 2 and 22 weeks after first Injection. Method of measurement: Using validated questionnaire of WOMAC Score.