Evaluation of efficacy of intra articular injection of mannitol in patient with knee osteoarthritis
Phase 3
- Conditions
- Osteoarthritis of knee.Osteoarthritis of knee
- Registration Number
- IRCT20190912044756N1
- Lead Sponsor
- Shiraz University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
Age: 38 to70 years old
Gender: male or female
Knee radiography anterior standing view have been for the last three month
Have symptoms of osteoartritis include pain, crepitation for at least a month without any extra articular involvment
Exclusion Criteria
Any injection of the knee joint during the last three of months
sensitivity reaction to test drug
The patient have done total knee arthroplasty
The patient have diseases mimicking the symptoms of knee pain such as neuropathy and radiculopathy
Diseases such as rheumatoid arthritis, Reiter's syndrom, gout
Uncontrolled diabetes,HBA1c more than7.5, BMI more than 40
History of knee trauma,fracture
Patient's mental disorder
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Knee pain. Timepoint: Two weeks ,foure weeks, eight weeks. Method of measurement: Visual Analogue Scale.
- Secondary Outcome Measures
Name Time Method Function of patient. Timepoint: two weeks, four weeks, eight weeks. Method of measurement: Oxford knee score.