Ocular complications, lagophthalmos, and dry eye in preseptal versus pretarsal botulinum toxin injection in benign essential blepharospasm

Not Applicable

• Conditions: Blepharospasm; Blepharospasm, preseptal injection, pretarsal injection, botulinum toxin, ocular complications, lagophthalmos, dry eye, efficacy

• Registration Number: TCTR20190807005
• Lead Sponsor: Ratchadapiseksompoh fund, Chulalongkorn university

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2019-08-07
• Study Completion: 2020-09-01
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Pending (Not yet recruiting)
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

Age ≥ 18 years old, and were diagnosed as blepharospasm by a neuroophthalmologist or neurologist.

Exclusion Criteria

Prior botulinum toxin injection less than 3 months, allergy to botulinum toxin

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Ocular complications, lagophthalmos, Dry eye At 1 and 3 months after injection Margin to reflex distance, lagophthalmos, tears break up time, ocular surface staining

Secondary Outcome Measures

Name	Time	Method
Efficacy At 1 and 3 months after injection Jankovic rating scale