Collection of Blood Samples From SMART Study Participants for Future Genetic Studies
- Conditions
- HIV Infections
- Registration Number
- NCT00377169
- Brief Summary
The purpose of this study is to collect blood samples from SMART study participants to use in future genetic studies.
- Detailed Description
Despite progress in the treatment of HIV and a greater understanding of the pathophysiology of HIV infection, there are still unexplained differences in both the progression of untreated HIV infection and response to antiretroviral therapy. These differences are likely related to the unique genetic makeup of individuals with HIV infection. Particular genes may offer protection against HIV infection, while other genes may make disease progression more likely. Knowing more about the genetic makeup of HIV infected individuals may lead to the development of a targeted treatment strategy based on an individual's specific risk of disease progression and sensitivity to medication toxicity. The purpose of this substudy is to collect blood samples from SMART study participants. The samples will be used in future Community Programs for Clinical Research on AIDS (CPCRA) studies investigating the link between human genetic factors and clinical outcome data.
This study will enroll individuals currently participating in the SMART study. Participants will provide one blood sample. Individual test results from future blood analyses will not be provided to a patient unless they may have profound health implications for that patient.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 3261
- Coenrollment in the SMART study
- Parent or guardian willing to provide informed consent, if applicable
Not provided
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (42)
AltaMed Health Services Corporation
🇺🇸Los Angeles, California, United States
Los Angeles Gay & Lesbian Community Service Center
🇺🇸Los Angeles, California, United States
VA Greater Los Angeles Healthcare System
🇺🇸Los Angeles, California, United States
VA Greater Loss Angeles Healthcare System
🇺🇸Los Angeles, California, United States
Comprehensive Care Center/North Broward Hospital
🇺🇸Ft. Lauderdale, Florida, United States
Hillsborough County Health Department
🇺🇸Tampa, Florida, United States
Absolute Care Clinic
🇺🇸Atlanta, Georgia, United States
AID Atlanta/Morehouse Medical School Ryan White Cl
🇺🇸Atlanta, Georgia, United States
AIDS Research Consortium of Atlanta (ARCA) Central
🇺🇸Atlanta, Georgia, United States
Dr. Dennis Melton (private practice)
🇺🇸Atlanta, Georgia, United States
Scroll for more (32 remaining)AltaMed Health Services Corporation🇺🇸Los Angeles, California, United States