Collection of Blood Samples From SMART Study Participants for Future Genetic Studies
- Conditions
- HIV Infections
- Registration Number
- NCT00377169
- Brief Summary
The purpose of this study is to collect blood samples from SMART study participants to use in future genetic studies.
- Detailed Description
Despite progress in the treatment of HIV and a greater understanding of the pathophysiology of HIV infection, there are still unexplained differences in both the progression of untreated HIV infection and response to antiretroviral therapy. These differences are likely related to the unique genetic makeup of individuals with HIV infection. Particular genes may offer protection against HIV infection, while other genes may make disease progression more likely. Knowing more about the genetic makeup of HIV infected individuals may lead to the development of a targeted treatment strategy based on an individual's specific risk of disease progression and sensitivity to medication toxicity. The purpose of this substudy is to collect blood samples from SMART study participants. The samples will be used in future Community Programs for Clinical Research on AIDS (CPCRA) studies investigating the link between human genetic factors and clinical outcome data.
This study will enroll individuals currently participating in the SMART study. Participants will provide one blood sample. Individual test results from future blood analyses will not be provided to a patient unless they may have profound health implications for that patient.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 3261
- Coenrollment in the SMART study
- Parent or guardian willing to provide informed consent, if applicable
Not provided
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (42)
Clinique Medicale L'actuel
🇨🇦Montreal, Quebec, Canada
Medizinische Universitatsklinik
🇬🇲Bonn, Gambia
Gladstone Road Medical Centre
🇦🇸Highgate Hill, American Samoa
Centro Hospital de Cascais
🇵🇹Cascais, Portugal
Hospital Joaquim Urbano
🇵🇹Porto, Portugal
Catedra de Enfermedades Infecciosas
🇺🇾Montevideo, Uruguay
Fundacion Arriaran Santa Elvira
🇨🇱Santiago, Chile
Helsinki University Central Hospital
🇫🇮Helsinki, Finland
AltaMed Health Services Corporation
🇺🇸Los Angeles, California, United States
Los Angeles Gay & Lesbian Community Service Center
🇺🇸Los Angeles, California, United States
VA Greater Los Angeles Healthcare System
🇺🇸Los Angeles, California, United States
Absolute Care Clinic
🇺🇸Atlanta, Georgia, United States
Westchester Medical Center/New York Medical College
🇺🇸Valhalla, New York, United States
VA Greater Loss Angeles Healthcare System
🇺🇸Los Angeles, California, United States
AID Atlanta/Morehouse Medical School Ryan White Cl
🇺🇸Atlanta, Georgia, United States
Hillsborough County Health Department
🇺🇸Tampa, Florida, United States
AIDS Research Consortium of Atlanta (ARCA) Central
🇺🇸Atlanta, Georgia, United States
Dr. Dennis Melton (private practice)
🇺🇸Atlanta, Georgia, United States
Dr. Melanie Thompson and Dr. Annette Bernard (private practice)
🇺🇸Atlanta, Georgia, United States
Dr. Richard Hudson (private practice)
🇺🇸Atlanta, Georgia, United States
Mayo Clinic/CORNET
🇺🇸Rochester, Minnesota, United States
Froedtert and Medical College I.D. Clinic
🇺🇸Milwaukee, Wisconsin, United States
Comprehensive Care Center/North Broward Hospital
🇺🇸Ft. Lauderdale, Florida, United States
SUNY Downstate Medical Center
🇺🇸Brooklyn, New York, United States
University of North Texas Health Science Center
🇺🇸Fort Worth, Texas, United States
Royal Melbourne Hospital
🇦🇺Parkville, Victoria, Australia
Royal Perth Hospital
🇦🇺Perth, Australia
Westmead Hospital
🇦🇺Westmead, Australia
C.H.U. St. Pierre Center Hospitalier Universitaire
🇧🇪Bruxelles, Belgium
Arbus Universitetshospital, Skejby Department of Infectious Diseases
🇩🇰Brendstrupgaardvej Aarhus, Denmark
Klinikum der Ruprecht-Karis-Universitat (U. Hospit)
🇬🇲Heidelberg, Gambia
ifi Institut
🇩🇪Hamburg, Germany
University Hospital Koln (Cologne)
🇩🇪Koln, Germany
AIDS Medical Center, International Medical Center
🇯🇵Tokyo, Japan
J.W. Goethe University Hospital
🇩🇪Frankfurt, Germany
Infektionsambulanz und Tagesklinik Poliklinik Innenstadt der
🇩🇪Munich, Germany
University Hospital Center Ibn Rochd
🇲🇦Casablanca, Morocco
Waikato Hospital
🇳🇿Hamilton, New Zealand
Christchurch Hospital
🇳🇿Christchurch, New Zealand
Wellington Hospital
🇳🇿New Town, Wellington, New Zealand
Hospital de Santa Maria
🇵🇹Lisbon, Portugal
Wroclaw University School of Medicine
🇵🇱Koszarowa, Poland