Preanalgesic Effect of Gabapentin in Total Knee Repair

Not Applicable

Completed

• Conditions: Pain
• Interventions: Drug: Gabapentin; Drug: Placebos

• Registration Number: NCT00279487
• Lead Sponsor: Texas Health Resources

Brief Summary

The purpose of this study is to determine whether gabapentin, as a one time administration prior to a total knee replacement procedure, has opioid sparing effects and a reduction in pain scores.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2006-01-16
• Study First Submitted QC: 2006-01-16
• Study First Posted: 2006-01-19
• Study Completion: 2007-08
• Status Verified: 2016-10
• Last Update Submitted: 2016-10-24
• Last Update Posted: 2016-10-26

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 24

Inclusion Criteria

• Patients undergoing total knee replacement who received pain management by the following modality:

  • Intravenous patient-controlled analgesia (IV-PCA) opioid
  • Local femoral nerve block with 1.5% mepivacaine 20 ml and 0.5% ropivacaine 20 ml

Exclusion Criteria

• Age < 18 years old

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Arm 1	Gabapentin	Patients will receive 1200mg gabapentin 1-2 hours prior to surgery.
Arm 2	Placebos	Patients will receive placebo 1-2 hours prior to surgery.

Trial Locations

Locations (1)

Presbyterian Hospital of Dallas; 🇺🇸 Dallas, Texas, United States