Measurement Skin Temperature During Pulsed Laser Exposure
- Conditions
- Port-Wine Stain
- Interventions
- Procedure: cooling spray during laser treatment
- Registration Number
- NCT00540917
- Lead Sponsor
- University of California, Irvine
- Brief Summary
Lasers are the treatment modality of choice for Port Wine Stain birthmarks.The epidermis is not totally spared due to partial absorption of energy therein by melanin that presents an optical barrier through which the light must pass to reach the underlying blood vessels. Absorption of laser energy by melanin causes localized heating in the epidermis, which may, if not controlled, produce permanent complications such as hypertrophic scarring or dyspigmentation.
- Detailed Description
The researchers want to establish a correlation between non-invasive skin temperature measurements and the minimum laser energy during skin laser treatment using cryogen spray cooling.
This study would eliminate the need for test pulses to estimate the safe and acceptable radiant exposure prior to laser treatment.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 118
- 7 years of age and older with diagnosis of port wine stain birthmark
- 18 years of age and older with no port wine stain
- non-pregnant women
- apparent good health
- age less than 7 years old
- pregnant women
- history of photodermatoses or skin cancer
- current use of photosensitizing drugs
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description cooling spray cooling spray during laser treatment cooling spray during laser treatment
- Primary Outcome Measures
Name Time Method skin temperature during laser treatment 90 days
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Beckman Laser Institute Medical Clinic University of California Irvine
🇺🇸Irvine, California, United States