DRKS00027889
Completed
Not Applicable
Muscle internal mechanics in individuals with generalized joint hypermobility (GJH): a comparison of patients with Hypermobility Spectrum Disorder/ Ehlers-Danlos Syndromes vs dancers vs healthy non-hypermobile control subjects Muscle mechanics in hypermobility - Myper
DLR - Institut für Luft- Und RaumfahrtAbteilung für für Muskel- und Knochenstoffwechsel0 sites48 target enrollmentMarch 15, 2022
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- healthy volunteers
- Sponsor
- DLR - Institut für Luft- Und RaumfahrtAbteilung für für Muskel- und Knochenstoffwechsel
- Enrollment
- 48
- Status
- Completed
- Last Updated
- last year
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •All groups:
- •\- Ability to consent
- •\- Consent and signed informed consent prior to study.
- •\- Group 1 (Monogenic EDS): Diagnosed with classic or classic\-like EDS.
- •According to the EDS diagnostic criteria 2017
- •\- Group 2 (HSD/ hEDS group): Diagnosed with hypermobile EDS or HSD according to the 2017
- •EDS diagnostic criteria 2017
- •\- Group 3 (dancers): active dancers who are gender, age, and height\-matched with
- •the participants of group 1
- •\- Group 4 (control subjects): healthy, non\-hypermobile non\-dancers who match the participants of group 1 in terms of their
Exclusion Criteria
- •\- Contraindications to magnetic resonance imaging (claustrophobia, implants).
- •\- Injury or illness in the past six weeks that interferes with calf muscle contractions or jump and hop testing
Outcomes
Primary Outcomes
Not specified
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