Dynamic arterial elastance for predicting mean arterial pressure responsiveness after fluid challenge in spontaneously breathing septic patients

Recruiting

• Conditions: Spontaneously breathing septic patient with Acute circulatory failure who is predicted fluid response by mini-fluid challenge test; dynamic arterial elastance; spontaneous breathing; sepsis; acute circulatory failure; fluid responsiveness

• Registration Number: TCTR20220517001
• Lead Sponsor: Faculty of Medicine Ramathibodi Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2022-05-17
• Study Completion: 2023-01-13
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

1. Spontaneously breathing septic patient
2. Acute circulatory failure
3. Fluid responsiveness (mini-fluid challenge using colloid 100mL or passive leg raising test : increase SV or CO greater than or equal to 10% )

Exclusion Criteria

1. Cardiac arrhythmia
2. Right heart failure
3. Using inotropic drug
4. Intraabdominal pressure > 12 mmHg
5. Heart rate to Respiratory rate ratio less than 3.6
6. Deny participation

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
sensitivity and specificity of Eadyn before fluid loading FloTrac connected to Hemosphere Monitoring

Secondary Outcome Measures

Name	Time	Method
Cut-point value of Eadyn before fluid loading FloTrac connected to Hemosphere Monitoring