Dynamic arterial elastance for predicting mean arterial pressure responsiveness after fluid challenges in acute respiratory distress syndrome patients

Not Applicable

Completed

• Conditions: Acute respiratory distress syndrome with acute circulatory failure; Dynamic arterial elastance; Acute respiratory distress syndrome (ARDS); Mean arterial pressure responsiveness; Fluid challenges

• Registration Number: TCTR20170306001
• Lead Sponsor: Faculty of Medicine Ramathibodi Hospital, Mahidol University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2017-03-06
• Study Completion: 2018-01-31
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 23

Inclusion Criteria

- Age >= 18 years
- ARDS; P/F ratio<300
- On mechanical ventilator with tidal volume < 8 ml/kg (predicted body weight)
- Acute circulatory failure
- Fluid responsiveness

Exclusion Criteria

- Arrhythmias
- low LVEF
- On Inotropic drugs
- Abdominal hypertension
- HR: RR<3.6

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Dynamic arterial elastance N/A Ratio of pulse pressure variation to stoke volume variation

Secondary Outcome Measures

Name	Time	Method
Predictive value N/A Cut point, sensitivity, specificity