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Oral Tanshinone in the treatment of dry eye associated with rosacea

Phase 1
Conditions
dry eye associated with rosacea
Registration Number
ITMCTR2100005326
Lead Sponsor
The Second Affiliated Hospital of Fujian Medical University
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Pending
Sex
All
Target Recruitment
Not specified
Inclusion Criteria

This study included patients who were diagnosed with rosacea at the dermatology clinic and met the ophthalmologic assessment for dry eye.

Exclusion Criteria

1.Trichiasis, eyelid abnormalities, lacrimal diseases, glaucoma or Uveitis, and other ophthalmic emergencies;
2.Other conjunctival or ocular surface diseases, such as conjunctival cyst, conjunctival pemphigoid, conjunctival relaxation, limbal stem cell deficiency, etc.
3.long-term use of topical drugs in addition to artificial tears, such as anti-glaucoma drugs, immunosuppressants, etc.
4.History of ocular trauma, eyelid, ocular surface, glaucoma and internal eye surgery;
5.Severe liver and kidney dysfunction, Coagulopathy, or other serious diseases may affect drug efficacy;
6.Pregnant women;
7.The researchers concluded that there were any conditions that were not suitable for participation in the trial.

Study & Design

Study Type
Treatment study
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Corneal sodium fluorescein staining;Non-invasive tear film breakup time;meibomian gland dropout;Schiemer I test;plugged meibomian gland orifices;
Secondary Outcome Measures
NameTimeMethod
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