Multi-modular Motion-assisted Memory Desensitization and Reconsolidation (3MDR) as treatment for Posttraumatic Stress Disorder

Completed

Conditions: Posttraumatic Stress Disorder
PTSD
10002861

Registration Number: NL-OMON44897

Lead Sponsor: Stichting Centrum '45

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Completed

Sex: Not specified

Target Recruitment: 40

Inclusion Criteria

-Current chronic combat-related Posttraumatic Stress Disorder (Clinician Administered PTSD Scale (CAPS) score > 50, for at least 3 months).
- Being treatment resistant for trauma-focused psychotherapeutic interventions, which means having been treated for PTSD for a minimum of 6 consecutive months, of which 3 months with trauma-focused therapy, for instance Eye-Movement Desensitization Reprocessing (EMDR), Brief Eclectic Psychotherapy (BEP), Narrative Exposure Therapy (NET) or Prolonged Exposure (PE) with weekly sessions of at least 45 minutes or two-weekly session of at least 90 minutes.

Exclusion Criteria

* Acute suicidality
* Difficulties walking, especially on a treadmill
* Current severe alcohol and/or substance dependence according to DSM-IV (patients are allowed to enter after initial treatment of this disorder).
* Acute psychosis.
* Patients must be stable on their current psychotropic medication for a period of 4 weeks before entering the trial and agree to not make changes in dosages or add any new medications during the course of the 3MDR treatment. In agreement with clinical guidelines patients were allowed to stop anxiolytic medication to better engage in trauma processing.

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Main study parameter is the difference between the two groups in change in PTSD<br /><br>symptom severity between start of the intervention and end of the study.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Other areas in which improvement is expected are perceived social support,<br /><br>anxiety in general, depressive symptoms, avoidance of thoughts and behaviors,<br /><br>and neuropsychological functioning (memory and attention). </p><br>