Social cognition in children treated for a brain tumour: A comparative prospective international multi-centre study

Recruitment & Eligibility

Status: Completed

Sex: Not specified

Target Recruitment: 39

Inclusion Criteria

Brain tumour patients:
1) Aged 5-12 years at first assessment
2) Newly diagnosed brain tumour patients that have not yet received adjuvant therapy
3) Stable medical condition;Healthy controls:
1) Aged 5-12 years at first assessment ;CF patients:
1) Aged 5-12 years at first assessment
2) Stable medical condition

Exclusion Criteria

Brain tumour patients:
1) Diagnosed with a disorder of the autistic spectrum, not related to the tumour (Autism, Asperger*s Syndrome or Pervasive Developmental Disorder not otherwise specified).
2) History of other brain disease or neurological condition interfering with normal development.
3) No native Dutch speaker
4) Severe sensory handicaps and/or behavioural problems interfering with reliable neuropsychological assessment
5) IQ below 70
6) Poor prognosis and life expectancy less than 1 year.;Healthy controls:
1) Diagnosed with a disorder of the autistic spectrum (Autism, Asperger*s Syndrome or Pervasive Developmental Disorder not otherwise specified).
2) History of other brain disease or neurological condition interfering with normal development.
3) No native Dutch speaker
4) Severe sensory handicaps and/or behavioural problems interfering with reliable neuropsychological assessment.
5) IQ below 70;CF patients:
1) Diagnosed with a disorder of the autistic spectrum (Autism, Asperger*s Syndrome or Pervasive Developmental Disorder not otherwise specified).
2) History of other brain disease or neurological condition interfering with normal development.
3) No native Dutch speaker
4) Severe sensory handicaps and/or behavioural problems interfering with reliable neuropsychological assessment.
5) IQ below 70

Study & Design

Study Type: Observational non invasive

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Change in performance on tests of social cognition from time 1 to time 2. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>1) Change in reports of social and emotional functioning of patients<br /><br>themselves, parents and teachers from time 1 to time 2.<br /><br>2) Influence of Individual medical characteristics on the change in performance<br /><br>on tests of social cognition from time 1 to time 2.<br /><br>3) Influence of Socio-economical status (parental education and occupation) on<br /><br>the change in performance on tests of social cognition from time 1 to time 2<br /><br>4) Influence of Intelligence level and Executive Functions on the change in<br /><br>performance on tests of social cognition from time 1 to time 2.</p><br>