The Effect of Calcium on Fecal Fat and Energy Excretion
试验速览
- 阶段
- 不适用
- 入组人数
- 15
- 试验地点
- 2
- 主要终点
- Fecal fat excretion, fecal energy excretion, calcium excretion, cholesterol
研究概览
简要总结
The overall purpose of this study is to examine the effect of calcium on fecal fat and energy excretion.
详细描述
Several reports have found inverse associations between calcium intake and body weight. Few intervention studies have shown that a high calcium diet resulted in a greater body weight loss than a low calcium diet. The mechanism is not clear, but one possible explanation is reduced absorption of fat in the gut, due to formation of insoluble calcium fatty acid soaps or binding of bile acids which impairs the formation of micelles.
The aim of this study is to examined if a high calcium intake from dairy products, in diets high or normal in fat content, have an effect on fecal energy and fat excretion, concentrations of substrates involved in energy metabolism and blood pressure.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 50 Years（Adult）
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •healthy meals
- •BMI 24-31 kg/m2
- •age between 18-50 years
排除标准
- •donation of blood 6 months before and under the study
- •milk allergy, diabetes, hypertension, hyperlipidemia, cronic infectious disease
- •use of dietary supplements 3 months before and under the study
- •elite athletes
- •use of medication
结局指标
主要结局
Fecal fat excretion, fecal energy excretion, calcium excretion, cholesterol
次要结局
- Vitamin D, changes in lipolyse