Effect of High-calcium Intake on Appetite, Insulinemia and Incretins

Not Applicable

Completed

• Conditions: Nutritional and Metabolic Diseases

• Registration Number: NCT01682343
• Lead Sponsor: Northumbria University

Brief Summary

The purpose of this study is to investigate the appetite, insulin and incretin hormone responses to a high-calcium meal.

Detailed Description

Participants will be provided with control and high-calcium meals. Insulin, appetite, glucagon-like peptide-1 and glucose-dependent insulinotropic peptide responses will be assessed, along with rates of substrate oxidation.

Study Timeline

• Study Start: 2012-05
• Primary Completion: 2012-08
• Study Completion: 2012-08
• Status Verified: 2012-09
• Study First Submitted: 2012-09-06
• Study First Submitted QC: 2012-09-06
• Study First Posted: 2012-09-10
• Last Update Submitted: 2012-09-10
• Last Update Posted: 2012-09-11

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Male
• Target Recruitment: 10

Inclusion Criteria

• recreationally active
• male

Exclusion Criteria

• food intolerances/allergies

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Primary Outcome Measures

Name	Time	Method
Subjective appetite ratings	3 hour	Subjective ratings of appetite assessed by visual analogue scales.

Secondary Outcome Measures

Name	Time	Method
Serum insulin concentration	2 hour	2 hour area under the curve for serum insulin following breakfast consumption
Plasma glucose-dependent insulinotropic peptide concentration	2 hour	2 hour area under the curve for plasma glucose-dependent insulinotropic peptide following breakfast consumption
Plasma glucagon-like peptide-1 concentration	2 hour	2 hour area under the curve for plasma glucagon-like peptide-1 following breakfast consumption

Trial Locations

Locations (1)

Northumbria University; 🇬🇧 Newcastle upon Tyne, Tyne on Wear, United Kingdom