Effect of treating human gum disease by local application of curenext(R) ointment containing turmeric extract.

Phase 4

Completed

• Registration Number: CTRI/2013/12/004223
• Lead Sponsor: Chhattisgarh Dental College and Research Institute

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 24 November 2021

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 60

Inclusion Criteria

Systemically healthy individuals

Possessing at atleast 20 natural teeth.

All the posterior teeth in upper right quadrant excluding the third molar should be present and exhibit periodontal health or gingivitis.

Exclusion Criteria

There should be no teeth with a probing depth > 3mm.

Participants with any tobacco use

Recent use of antibiotics, aspirin or non-steroidal anti-inflammatory drugs (NSAIDs) during past one month.

If they necrotizing periodontal conditions, gross oral pathology, severe unrestored dental caries or clinically significant laboratory abnormalities.

Pregnant and lactating mothers

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
assessment of IL1 β/ ccl28 levels in Gingival crevicular fluidTimepoint: 0 days. 29 days

Secondary Outcome Measures

Name	Time	Method
1. Plaque index (Silness and Loe) <br/ ><br>2. Modified Gingival Index (Loe and Sillness Index) <br/ ><br>3. Bleeding on probingTimepoint: 0 days. 29 days