atural killer cell receptor variability during the menstrual cycle
Recruiting
- Conditions
- ot applicable
- Registration Number
- NL-OMON29470
- Lead Sponsor
- Academic Hospital Maastricht, Department of Obstetrics and Gynaecology
- Brief Summary
ot applicable
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 12
Inclusion Criteria
Group 1: healthy women (no chronic medical conditions like chronic hypertension, chronic kidney failure, chronic immune conditions (SLE) or chronic medication use) with a regular natural menstrual cycle of 28 days (+/- 3 days), defined by no contraceptive use or healthy women with a copper spiral
Group 2: healthy men (no chronic medical conditions, like chronic hypertension, chronic kidney failure, chronic immune conditions (SLE) or chronic medication use)
Exclusion Criteria
- Current or recent (<2 weeks) symptomatic infection
- Previous pregnancy with complications, such as repeated miscarriages, preeclampsia, or diabetes gravidarum
- Unable to give mentally capable consent in Dutch
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Percentage of NK cells with activating and inhibitory receptors in peripheral blood
- Secondary Outcome Measures
Name Time Method Percentage of NK cells with activating and inhibitory receptors in menstrual blood