Study of the Diaphragmatic Function by Transient Elastography (ELASTODIAPH)

Not Applicable

Completed

• Conditions: Healthy
• Interventions: Diagnostic Test: Ultrasound

• Registration Number: NCT03313141
• Lead Sponsor: Association pour le Développement et l'Organisation de la Recherche en Pneumologie et sur le Sommeil

Brief Summary

The study of diaphragmatic function is usually measured by the pressures and volumes generated by contraction of the diaphragm, which is often difficult (cumbersome technique, difficulty to obtain a perfect cooperation of the subjects, and difficulty to specifically analyze the diaphragm compared to other accessory respiratory muscle groups). In this study, the investigators aimed at analysing diaphragmatic function by measuring the shortening, stiffness, strain and thickening of the diaphragm by ultrasound.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2017-10-04
• Study Start: 2017-10-09
• Study First Submitted QC: 2017-10-17
• Study First Posted: 2017-10-18
• Primary Completion: 2017-10-27
• Study Completion: 2017-10-27
• Status Verified: 2017-12
• Last Update Submitted: 2017-12-15
• Last Update Posted: 2017-12-19

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 14

Inclusion Criteria

• healthy volunteer

Exclusion Criteria

• chronic respiratory, neurologic or cardiac disease
• swallowing disorders
• pregnancy

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Subjects	Ultrasound	Only one arm is considered

Primary Outcome Measures

Name	Time	Method
Transdiaphragmatic pressure	2 hours	The transdiaphragmatic pressure is the sum of absolute values of gastric and oesophagal pressures

Trial Locations

Locations (1)

Pitie Salpêtrière Hospital; 🇫🇷 Paris, France