Role of Beta Trace Protein Assay During Spinal Anesthesia of Cesarean Section
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 90
- 试验地点
- 2
- 主要终点
- CSF sample: serum sample
研究概览
简要总结
Beta trace protein assay is an indicator of post-spinal CSF leak that predicts the degree of post-spinal headache.
详细描述
Beta trace protein is specific for CSF only and it is a quantitative analytic test.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Health Services Research
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 45 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •18-45 years old
- •free medical history.
- •free obstetric history.
排除标准
- •high risk pregnancy.
结局指标
主要结局
CSF sample: serum sample
时间窗: One year
After insertion of an intravenous line 4 ml serum will be collected, then 0.5 ml CSF sample will be collected after insertion of the dura by the selected spinal needle before injecting the anesthetic drugs used for spinal anesthesia. Beta trace protein assay will be measured through ELISA technique in both CSF and serum samples and the ratio will be calculated and measured. This ratio will be measured for the three arms aiming at the comparison between the three devices regarding the CSF : Serum ratio.
次要结局
未报告次要终点
研究者
Reham Ali Abdelhaleem Abdelrahman
Principal Investigator
Cairo University