Clinical study on the actual effect of Qishishengjiangguiyuan granule in the treatment of gastroesophageal reflux disease based on the real world
- Conditions
- Gastroesophageal reflux disease
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- Not specified
1. Those who meet the diagnostic criteria of GERD;
2. Aged 18 to 70 years;
3. Those who have not participated in other clinical research within 1 month;
4. After sufficient communication, voluntarily participate in this project and sign an informed consent.
1. Those who have severe spinal trauma and skin burns;
2. People with severe peptic ulcer, history of gastrointestinal surgery, gastrointestinal space-occupying lesions and other serious complications;
3. Pregnant or lactating women;
4. Patients with severe liver and kidney insufficiency, malignant tumors, who cannot tolerate gastroscopy as assessed by clinicians;
5. People with other diseases such as immunity and organ failure;
6. Merge mental patients who cannot control and may hurt others;
7. Those who have other serious infectious diseases, such as tuberculosis, anti-HIV positive;
8. Patients who have taken medicines (such as Probensine, Belladonna, Atropine, Aminophylline, Niacin, Diazepam, Valium, etc.) that can reduce the tension of the lower esophageal sphincter in the past week.
Study & Design
- Study Type
- Interventional study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Quality of life score;Recurrence rate; clinically effective rate;
- Secondary Outcome Measures
Name Time Method Gastroscopy diagnosis and classification;Extraesophageal symptoms;Gastroesophageal reflux symptoms;Anxiety and depression;Evaluation of the curative effect of Chinese Medicine symptoms of gastroesophageal reflux disease;