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Evaluation of curative effect and safety of Qinji Liangxue mixture on hemorrhagic internal hemorrhoids of excess heat type based on ultrasonic elastography

Phase 1
Conditions
Internal hemorrhoids
Registration Number
ITMCTR2000004002
Lead Sponsor
Shanghai Municipal Hospital of Traditional Chinese Medicine Affiliated to Shanghai University of Traditional Chinese Medicine
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Pending
Sex
All
Target Recruitment
Not specified
Inclusion Criteria

1. Patients with grade I and II internal hemorrhoids who meet the above diagnostic criteria, and the bleeding symptoms do not exceed 7 days.
2. Those who meet the above diagnostic criteria of TCM syndromes, such as heat stasis syndrome or dampness heat stagnation syndrome.
3. The age is between 18 and 75 years old.
4. The hemorrhoid mucosa congestion, erosion or bleeding point can be seen by anoscopy.
5. Those who voluntarily join the experiment and sign the informed consent form.

Exclusion Criteria

1. Patients with anal fissure, anal fistula, inflammatory bowel disease, blood disease, diabetes, colorectal cancer and other diseases and mental diseases.
2. Pregnant or lactating women.
3. Those who have used the related drugs (including oral drugs and local drugs) for the treatment of internal hemorrhoid bleeding in the past week.
4. Taking anticoagulant drugs, antiplatelet aggregation drugs, hormones, non steroidal analgesics and other drugs that affect the anticoagulant function.
5. Abnormal blood and urine routine, Pt, APTT, AST, alt, AKP, TBIL, bun, SCR, ECG.

Study & Design

Study Type
Interventional study
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Disappearance rate of hematochezia after 7 days of treatment;Remission time of hematochezia;Evaluation of transrectal ultrasound elastography;Stop time of hematochezia;
Secondary Outcome Measures
NameTimeMethod
Defecation score;
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