Combination Chemotherapy in Treating Patients With Bladder Cancer
- Conditions
- Bladder Cancer
- Interventions
- Registration Number
- NCT00014534
- Lead Sponsor
- Alliance for Clinical Trials in Oncology
- Brief Summary
RATIONALE: Drugs used in chemotherapy work in different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells.
PURPOSE: Randomized phase III trial to compare different combination chemotherapy regimens in treating patients who have advanced bladder cancer.
- Detailed Description
OBJECTIVES:
Primary
* Compare the survival of patients with completely resected locally advanced transitional cell carcinoma of the bladder treated with adjuvant doxorubicin and gemcitabine followed by paclitaxel and cisplatin vs adjuvant cisplatin and gemcitabine.
Secondary
* Compare the toxicity profiles of these regimens in these patients.
OUTLINE: This is a randomized study. Patients are stratified according to primary tumor status (\<T4 vs T4), number of positive lymph nodes (0 or unknown vs 1-5 vs \>5), and number of dissected nodes (0-10 or unknown vs \> 10). Patients are randomized to one of two treatment arms.
* Arm I: Patients receive adjuvant gemcitabine IV over 30 minutes on days 1, 8, and 15 and cisplatin IV over 30-60 minutes on day 1. Treatment repeats every 4 weeks for up to 4 courses in the absence of disease progression or unacceptable toxicity.
* Arm II: Patients receive adjuvant doxorubicin IV over 45 minutes followed by gemcitabine IV over 2 hours on day 1. Patients also receive filgrastim (G-CSF) subcutaneously (SC) daily on days 3-10. Treatment repeats every 14 days for up to 4 courses in the absence of disease progression or unacceptable toxicity. Beginning 14 days after the completion of doxorubicin and gemcitabine, patients receive paclitaxel IV over 3 hours and cisplatin IV over 20-30 minutes on day 1. Patients also receive G-CSF SC daily on days 3-10 or 4-11. Treatment repeats every 14 days for up to 4 courses in the absence of disease progression or unacceptable toxicity.
Patients are followed every 3 months for 18 months, every 6 months for 18 months, and then annually thereafter.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 42
Not provided
Not provided
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Gemcitabine + cisplatin cisplatin - Gemcitabine + Doxorubicin + Pegfilgrastim filgrastim - Gemcitabine + Doxorubicin + Pegfilgrastim doxorubicin hydrochloride - Gemcitabine + cisplatin gemcitabine hydrochloride - Gemcitabine + Doxorubicin + Pegfilgrastim gemcitabine hydrochloride -
- Primary Outcome Measures
Name Time Method Overall survival 4 years
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (285)
Geisinger Medical Group
🇺🇸State College, Pennsylvania, United States
William N. Wishard Memorial Hospital
🇺🇸Indianapolis, Indiana, United States
Rebecca and John Moores UCSD Cancer Center
🇺🇸San Diego, California, United States
Kaiser Permanente Medical Office -Vandever Medical Office
🇺🇸San Diego, California, United States
Veterans Affairs Medical Center - San Diego
🇺🇸San Diego, California, United States
Virginia Piper Cancer Institute at Abbott-Northwestern Hospital
🇺🇸Minneapolis, Minnesota, United States
Hennepin County Medical Center - Minneapolis
🇺🇸Minneapolis, Minnesota, United States
Arkansas Cancer Research Center at University of Arkansas for Medical Sciences
🇺🇸Little Rock, Arkansas, United States
Beebe Medical Center
🇺🇸Lewes, Delaware, United States
Walter Reed Army Medical Center
🇺🇸Washington, District of Columbia, United States
Ella Milbank Foshay Cancer Center at Jupiter Medical Center
🇺🇸Jupiter, Florida, United States
Mayo Clinic - Jacksonville
🇺🇸Jacksonville, Florida, United States
Watson Clinic
🇺🇸Lakeland, Florida, United States
CCOP - Mount Sinai Medical Center
🇺🇸Miami Beach, Florida, United States
Emory University Hospital - Atlanta
🇺🇸Altanta, Georgia, United States
Hematology and Oncology of Northeast Georgia
🇺🇸Athens, Georgia, United States
MBCCOP-Medical College of Georgia Cancer Center
🇺🇸Augusta, Georgia, United States
John B. Amos Community Cancer Center
🇺🇸Columbus, Georgia, United States
Rush-Copley Cancer Care Center
🇺🇸Aurora, Illinois, United States
St. Joseph Medical Center
🇺🇸Bloomington, Illinois, United States
Graham Hospital
🇺🇸Canton, Illinois, United States
Eureka Hospital
🇺🇸Eureka, Illinois, United States
Louis A. Weiss Memorial Hospital
🇺🇸Chicago, Illinois, United States
Galesburg Cottage Hospital
🇺🇸Galesburg, Illinois, United States
Mason District Hospital
🇺🇸Havana, Illinois, United States
InterCommunity Cancer Center of Western Illinois
🇺🇸Galesburg, Illinois, United States
Hopedale Medical Complex
🇺🇸Hopedale, Illinois, United States
Provena St. Mary's Wasser Regional Cancer Center - Kankakee
🇺🇸Kankakee, Illinois, United States
Community Cancer Center
🇺🇸Normal, Illinois, United States
Cardinal Bernardin Cancer Center at Loyola University Medical Center
🇺🇸Maywood, Illinois, United States
Kewanee Hospital
🇺🇸Kewanee, Illinois, United States
BroMenn Regional Medical Center
🇺🇸Normal, Illinois, United States
Community Hospital of Ottawa
🇺🇸Ottawa, Illinois, United States
Cancer Treatment Center at Pekin Hospital
🇺🇸Pekin, Illinois, United States
Methodist Medical Center of Illinois
🇺🇸Peoria, Illinois, United States
Oncology Hematology Associates of Central Illinois - Ottawa
🇺🇸Ottawa, Illinois, United States
Illinois Valley Community Hospital
🇺🇸Peru, Illinois, United States
Perry Memorial Hospital
🇺🇸Princeton, Illinois, United States
Oncology/Hematology Associates of Central Illinois, P.C.
🇺🇸Peoria, Illinois, United States
OSF St. Francis Medical Center
🇺🇸Peoria, Illinois, United States
Proctor Hospital
🇺🇸Peoria, Illinois, United States
Valley Cancer Center
🇺🇸Spring Valley, Illinois, United States
Regional Cancer Center at Memorial Medical Center
🇺🇸Springfield, Illinois, United States
Carle Cancer Center at Carle Foundation Hospital
🇺🇸Urbana, Illinois, United States
CCOP - Carle Cancer Center
🇺🇸Urbana, Illinois, United States
Indiana University Cancer Center
🇺🇸Indianapolis, Indiana, United States
Elkhart General Hospital
🇺🇸Elkhart, Indiana, United States
Saint Anthony Memorial Health Centers
🇺🇸Michigan City, Indiana, United States
Center for Cancer Therapy at LaPorte Hospital and Health Services
🇺🇸La Porte, Indiana, United States
McFarland Clinic, P.C.
🇺🇸Ames, Iowa, United States
Saint Joseph Regional Medical Center - Plymouth Campus
🇺🇸Plymouth, Indiana, United States
Memorial Hospital of South Bend
🇺🇸South Bend, Indiana, United States
St. Luke's Hospital
🇺🇸Cedar Rapids, Iowa, United States
Mercy Cancer Center at Mercy Medical Center
🇺🇸Cedar Rapids, Iowa, United States
Genesis Regional Cancer Center at Genesis Medical Center
🇺🇸Davenport, Iowa, United States
Cedar Rapids Oncology Associates
🇺🇸Cedar Rapids, Iowa, United States
CCOP - Iowa Oncology Research Association
🇺🇸Des Moines, Iowa, United States
Genesis Medical Center - West Campus
🇺🇸Davenport, Iowa, United States
Medical Oncology and Hematology Associates at John Stoddard Cancer Center
🇺🇸Des Moines, Iowa, United States
Fairview Ridges Hospital
🇺🇸Burnsville, Minnesota, United States
Mercy and Unity Cancer Center at Mercy and Unity Hospitals
🇺🇸Fridley, Minnesota, United States
Veterans Affairs Medical Center - Minneapolis
🇺🇸Minneapolis, Minnesota, United States
Fairview Southdale Hospital
🇺🇸Edina, Minnesota, United States
St. John's Hospital
🇺🇸Maplewood, Minnesota, United States
St. John's Regional Health Center
🇺🇸Springfield, Missouri, United States
St. Joseph's Hospital
🇺🇸St Paul, Minnesota, United States
Saint Francis Cancer Center
🇺🇸Shakopee, Minnesota, United States
Bozeman Deaconess Hospital
🇺🇸Bozeman, Montana, United States
Fox Chase Virtua Health Cancer Program at Virtua West Jersey
🇺🇸Voorhees, New Jersey, United States
Charles R. Wood Cancer Center at Glens Falls Hospital
🇺🇸Glens Falls, New York, United States
Veterans Affairs Medical Center - Syracuse
🇺🇸Syracuse, New York, United States
Annie Penn Cancer Center
🇺🇸Reidsville, North Carolina, United States
John Smith, Jr./Dalton McMichael Cancer Center at Morehead Memorial Hospital
🇺🇸Eden, North Carolina, United States
Arthur G. James Cancer Hospital and Solove Research Institute at Ohio State University
🇺🇸Columbus, Ohio, United States
Cleveland Clinic Taussig Cancer Center
🇺🇸Cleveland, Ohio, United States
Grandview Hospital
🇺🇸Dayton, Ohio, United States
Samaritan North Cancer Care Center
🇺🇸Dayton, Ohio, United States
Community Oncology Group - Independence
🇺🇸Independence, Ohio, United States
Grady Memorial Hospital
🇺🇸Delaware, Ohio, United States
Ruth G. McMillan Cancer Center at Greene Memorial Hospital
🇺🇸Xenia, Ohio, United States
St. Joseph Health Care Center
🇺🇸Warren, Ohio, United States
St. Elizabeth Cancer Center at St. Elizabeth Health Center - Youngstown
🇺🇸Youngstown, Ohio, United States
Riddle Memorial Hospital
🇺🇸Media, Pennsylvania, United States
Joan Karnell Cancer Center at Pennsylvania Hospital
🇺🇸Philadelphia, Pennsylvania, United States
Miriam Hospital at Lifespan
🇺🇸Providence, Rhode Island, United States
Geisinger Wyoming Valley Medical Center
🇺🇸Wilkes-Barre, Pennsylvania, United States
Providence Cancer Center at Sacred Heart Medical Center
🇺🇸Spokane, Washington, United States
Danville Regional Medical Center
🇺🇸Danville, Virginia, United States
Providence Cancer Center at Holy Family Hospital
🇺🇸Spokane, Washington, United States
West Virginia University - Robert C. Byrd Health Sciences Center - Charleston Division
🇺🇸Charleston, West Virginia, United States
Mary Babb Randolph Cancer Center at West Virginia University Hospitals
🇺🇸Morgantown, West Virginia, United States
Gundersen Lutheran Cancer Center at Gundersen Lutheran Medical Center
🇺🇸La Crosse, Wisconsin, United States
Marshfield Clinic - Marshfield Center
🇺🇸Marshfield, Wisconsin, United States
Associates in Womens Health
🇺🇸Wichita, Kansas, United States
Cancer Center of Kansas, P.A.
🇺🇸Wichita, Kansas, United States
Cancer Center of Kansas, P.A. - El Dorado
🇺🇸El Dorado, Kansas, United States
North Suburban Medical Center
🇺🇸Thorton, Colorado, United States
Hope Cancer Care Center at Longmont United Hospital
🇺🇸Longmont, Colorado, United States
Pratt Cancer Center of Kansas
🇺🇸Pratt, Kansas, United States
Mid Dakota Clinic, P.C.
🇺🇸Bismarck, North Dakota, United States
Cancer Center of Kansas - Newton
🇺🇸Newton, Kansas, United States
Cancer Center of Kansas - Winfield
🇺🇸Winfield, Kansas, United States
Bismarck Cancer Center
🇺🇸Bismarck, North Dakota, United States
Cancer Center of Kansas, P.A. - Wichita
🇺🇸Wichita, Kansas, United States
CCOP - Wichita
🇺🇸Wichita, Kansas, United States
Southwest Medical Center
🇺🇸Liberal, Kansas, United States
University Medical Center of Southern Nevada
🇺🇸Las Vegas, Nevada, United States
Sletten Regional Cancer Institute
🇺🇸Great Falls, Montana, United States
Montana Cancer Center at St. Patrick Hospital and Health Sciences Center
🇺🇸Missoula, Montana, United States
Bon Secours St. Francis Health System
🇺🇸Greenville, South Carolina, United States
Veterans Affairs Medical Center - East Orange
🇺🇸East Orange, New Jersey, United States
Cancer Institute of New Jersey at Hamilton
🇺🇸Hamilton, New Jersey, United States
Kalispell Regional Medical Center
🇺🇸Kalispell, Montana, United States
Fox Chase Virtua Health Cancer Program - Marlton
🇺🇸Marlton, New Jersey, United States
West Michigan Cancer Center
🇺🇸Kalamazoo, Michigan, United States
Great Falls Clinic
🇺🇸Great Falls, Montana, United States
Deaconess Billings Clinic - Downtown
🇺🇸Billings, Montana, United States
Cancer Institute of New Jersey at the Cooper University Hospital
🇺🇸Camden, New Jersey, United States
Bronson Methodist Hospital
🇺🇸Kalamazoo, Michigan, United States
Maine Center for Cancer Medicine and Blood Disorders - Scarborough
🇺🇸Scarborough, Maine, United States
CCOP - Northern New Jersey
🇺🇸Hackensack, New Jersey, United States
Cancer Institute of New Jersey at UMDNJ - Robert Wood Johnson Medical School
🇺🇸New Brunswick, New Jersey, United States
UW Health Oncology
🇺🇸Madison, Wisconsin, United States
St. James Community Hospital
🇺🇸Butte, Montana, United States
CCOP - Southern Nevada Cancer Research Foundation
🇺🇸Las Vegas, Nevada, United States
Community Medical Center
🇺🇸Missoula, Montana, United States
St. Peter's Hospital
🇺🇸Helena, Montana, United States
St. Mary's Medical Center
🇺🇸Huntington, West Virginia, United States
Eastern Montana Cancer Center
🇺🇸Miles City, Montana, United States
Medical X-Ray Center
🇺🇸Sioux Falls, South Dakota, United States
CCOP - Upstate Carolina
🇺🇸Spartanburg, South Carolina, United States
Avera McKennan Hospital and University Health Center
🇺🇸Sioux Falls, South Dakota, United States
UCSF Comprehensive Cancer Center
🇺🇸San Francisco, California, United States
Veterans Affairs Medical Center - San Francisco
🇺🇸San Francisco, California, United States
Presbyterian - St. Luke's Medical Center
🇺🇸Denver, Colorado, United States
Rose Medical Center
🇺🇸Denver, Colorado, United States
CCOP - Colorado Cancer Research Program, Incorporated
🇺🇸Denver, Colorado, United States
Oklahoma University Medical Center
🇺🇸Oklahoma City, Oklahoma, United States
Vanderbilt-Ingram Cancer Center at Vanderbilt Medical Center
🇺🇸Nashville, Tennessee, United States
Poudre Valley Hospital
🇺🇸Fort Collins, Colorado, United States
CCOP - Mayo Clinic Scottsdale Oncology Program
🇺🇸Scottsdale, Arizona, United States
Penrose Cancer Center at Penrose Hospital
🇺🇸Colorado Springs, Colorado, United States
CCOP - Christiana Care Health Services
🇺🇸Newark, Delaware, United States
Arroyo Grande Community Hospital
🇺🇸Arroyo Grande, California, United States
Swedish Medical Center
🇺🇸Englewood, Colorado, United States
Sky Ridge Medical Center
🇺🇸Lone Tree, Colorado, United States
St. Joseph Hospital
🇺🇸Denver, Colorado, United States
Front Range Cancer Specialists
🇺🇸Fort Collins, Colorado, United States
St. Mary-Corwin Regional Medical Center
🇺🇸Pueblo, Colorado, United States
Lombardi Cancer Center at Georgetown University Medical Center
🇺🇸Washington, District of Columbia, United States
Lynn Regional Cancer Center of Boca Raton Community Hospital
🇺🇸Boca Raton, Florida, United States
St. Francis Hospital
🇺🇸Wilmington, Delaware, United States
Memorial Cancer Institute at Memorial Regional Hospital
🇺🇸Hollywood, Florida, United States
Phoebe Cancer Center at Phoebe Putney Memorial Hospital
🇺🇸Albany, Georgia, United States
Curtis & Elizabeth Anderson Cancer Institute at Memorial Health University Medical Center
🇺🇸Savannah, Georgia, United States
University of Chicago Cancer Research Center
🇺🇸Chicago, Illinois, United States
Galesburg Clinic
🇺🇸Galesburg, Illinois, United States
Joliet Oncology Hematology Associates, Limited - West
🇺🇸Joliet, Illinois, United States
McDonough District Hospital
🇺🇸Macomb, Illinois, United States
CCOP - Illinois Oncology Research Association
🇺🇸Peoria, Illinois, United States
Cancer Center of Kansas - Chanute
🇺🇸Chanute, Kansas, United States
CCOP - Northern Indiana CR Consortium
🇺🇸South Bend, Indiana, United States
Mercy Capitol Hospital
🇺🇸Des Moines, Iowa, United States
Mercy Cancer Center at Mercy Medical Center - Des Moines
🇺🇸Des Moines, Iowa, United States
Meeker County Memorial Hospital
🇺🇸Litchfield, Minnesota, United States
Medical Oncology and Hematology Associates - West Des Moines
🇺🇸West Des Moines, Iowa, United States
Cancer Center of Kansas - Kingman
🇺🇸Kingman, Kansas, United States
Holden Comprehensive Cancer Center at University of Iowa
🇺🇸Iowa City, Iowa, United States
Cancer Center of Kansas - Dodge City
🇺🇸Dodge City, Kansas, United States
Borgess Medical Center
🇺🇸Kalamazooaa, Michigan, United States
Medical Oncology and Hematology Associates at Mercy Cancer Center
🇺🇸Des Moines, Iowa, United States
Mercy Medical Center - Sioux City
🇺🇸Sioux City, Iowa, United States
Cancer Center of Kansas - Salina
🇺🇸Salina, Kansas, United States
John Stoddard Cancer Center at Iowa Lutheran Hospital
🇺🇸Des Moines, Iowa, United States
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
🇺🇸Baltimore, Maryland, United States
Cancer Center of Kansas - Wellington
🇺🇸Wellington, Kansas, United States
Central Maine Medical Center
🇺🇸Lewiston, Maine, United States
St. Vincent Healthcare
🇺🇸Billings, Montana, United States
Cancer Center of Kansas, P.A. - Parsons
🇺🇸Parsons, Kansas, United States
Lawrence Memorial Hospital of Medford
🇺🇸Medford, Massachusetts, United States
Hulston Cancer Center at Cox Medical Center South
🇺🇸Springfield, Missouri, United States
Union Hospital Cancer Center at Union Hospital
🇺🇸Elkton MD, Maryland, United States
United Hospital
🇺🇸St. Paul, Minnesota, United States
Hutchinson Area Health Care
🇺🇸Hutchinson, Minnesota, United States
Hubert H. Humphrey Cancer Center at North Memorial Medical Center
🇺🇸Robbinsdale, Minnesota, United States
Missouri Cancer Associates
🇺🇸Columbia, Missouri, United States
James P. Wilmot Cancer Center at University of Rochester Medical Center
🇺🇸Rochester, New York, United States
CCOP - Metro-Minnesota
🇺🇸Saint Louis Park, Minnesota, United States
Randolph Hospital
🇺🇸Asheboro, North Carolina, United States
St. Anthony's Cancer Center
🇺🇸St. Louis, Missouri, United States
CCOP - Montana Cancer Consortium
🇺🇸Billings, Montana, United States
Deaconess Billings Clinic Cancer Center
🇺🇸Billings, Montana, United States
Roswell Park Cancer Institute
🇺🇸Buffalo, New York, United States
Batte Cancer Center at Northeast Medical Center
🇺🇸Concord, North Carolina, United States
Long Island Cancer Center at Stony Brook University Hospital
🇺🇸Stony Brook, New York, United States
Rutherford Hospital
🇺🇸Rutherfordton, North Carolina, United States
Community General Hospital of Greater Syracuse
🇺🇸Syracuse, New York, United States
Medcenter One Health System
🇺🇸Bismarck, North Dakota, United States
Wayne Memorial Hospital, Incorporated
🇺🇸Goldsboro, North Carolina, United States
Duke Comprehensive Cancer Center
🇺🇸Durham, North Carolina, United States
Ireland Cancer Center at University Hospitals of Cleveland and Case Western Reserve University
🇺🇸Cleveland, Ohio, United States
Miami Valley Hospital
🇺🇸Dayton, Ohio, United States
St. Alexius Medical Center
🇺🇸Bismarck, North Dakota, United States
Cancer Treatment Center at Merle West Medical Center
🇺🇸Klamath Falls, Oregon, United States
Legacy Mount Hood Medical Center
🇺🇸Glesham, Oregon, United States
St. Elizabeth Boardman Cancer Center
🇺🇸Boardman, Ohio, United States
Comprehensive Cancer Center at Legacy Good Samaritan Hospital & Medical Center
🇺🇸Portland, Oregon, United States
CCOP - Columbia River Oncology Program
🇺🇸Portland, Oregon, United States
Mercy Medical Center Oncology Unit
🇺🇸Springfield, Ohio, United States
Veterans Affairs Medical Center - Dayton
🇺🇸Dayton, Ohio, United States
Mount Carmel West Hospital
🇺🇸Columbus, Ohio, United States
Charles F. Kettering Memorial Hospital
🇺🇸Kettering, Ohio, United States
Institute of Oncology at Vilnius University
🇺🇸Portland, Oregon, United States
CCOP - Dayton
🇺🇸Dayton, Ohio, United States
Providence Milwaukie Hospital
🇺🇸Milwaukie, Oregon, United States
Legacy Meridian Park Hospital
🇺🇸Tualatin, Oregon, United States
Providence St. Vincent Medical Center
🇺🇸Portland, Oregon, United States
Providence Cancer Center at Providence Portland Medical Center
🇺🇸Portland, Oregon, United States
Lewistown Hospital
🇺🇸Lewistown, Pennsylvania, United States
Central Pennsylvania Hematology and Medical Oncology Associates, PC
🇺🇸Lemoyne, Pennsylvania, United States
Abramson Cancer Center of the University of Pennsylvania
🇺🇸Philadelphia, Pennsylvania, United States
Greenville Hospital System Cancer Center
🇺🇸Greenville, South Carolina, United States
Sioux Valley Hospital and University of South Dakota Medical Center
🇺🇸Sioux Falls, South Dakota, United States
Cancer Center at Southwest Washington Medical Center
🇺🇸Vancouver, Washington, United States
CCOP - Greenville
🇺🇸Greenville, South Carolina, United States
Medical College of Wisconsin Cancer Center
🇺🇸Milwaukee, Wisconsin, United States
University of Wisconsin Comprehensive Cancer Center
🇺🇸Madison, Wisconsin, United States
Fox Valley Hematology and Oncology
🇺🇸Appleton, Wisconsin, United States
University of Wisconsin Cancer Center at Aspirus Wausau Hospital
🇺🇸Wausau, Wisconsin, United States
Welch Cancer Center
🇺🇸Sheridan, Wyoming, United States
Boulder Community Hospital
🇺🇸Boulder, Colorado, United States
Porter Adventist Hospital
🇺🇸Denver, Colorado, United States
Aurora Presbyterian Hospital
🇺🇸Aurora, Colorado, United States
Mayo Clinic Cancer Center
🇺🇸Rochester, Minnesota, United States
Cancer Care Center at Regions Hospital
🇺🇸Saint Paul, Minnesota, United States
Park Nicollet Clinic
🇺🇸St. Louis Park, Minnesota, United States
Ridgeview Medical Center
🇺🇸Waconia, Minnesota, United States
Woodwinds Hospital
🇺🇸Woodbury, Minnesota, United States
Michael & Dianne Bienes Comprehensive Cancer Center at Holy Cross Hospital
🇺🇸Fort Lauderdale, Florida, United States
St. Margaret's Hospital
🇺🇸Spring Valley, Illinois, United States
St. Francis Hospital and Health Centers
🇺🇸Beech Grove, Indiana, United States
Wendt Regional Cancer Center at Finley Hospital
🇺🇸Dubuque, Iowa, United States
Siouxland Regional Cancer Center
🇺🇸Sioux City, Iowa, United States
Siouxland Hematology-Oncology Associates
🇺🇸Sioux City, Iowa, United States
St. Luke's Regional Medical Center
🇺🇸Sioux City, Iowa, United States
Lenoir Memorial Cancer Center
🇺🇸Kinston, North Carolina, United States
Moses Cone Regional Cancer Center at Wesley Long Community Hospital
🇺🇸Greensboro, North Carolina, United States
Akron City Hospital at Summa Health System
🇺🇸Akron, Ohio, United States
Wilson Medical Center
🇺🇸Wilson, North Carolina, United States
Adena Regional Medical Center
🇺🇸Chillicothe, Ohio, United States
Riverside Methodist Hospital Cancer Care
🇺🇸Columbus, Ohio, United States
CCOP - Columbus
🇺🇸Columbus, Ohio, United States
Grant Riverside Cancer Services
🇺🇸Columbus, Ohio, United States
Doctors Hospital at Ohio Health
🇺🇸Columbus, Ohio, United States
Good Samaritan Hospital
🇺🇸Dayton, Ohio, United States
Fairfield Medical Center
🇺🇸Lancaster, Ohio, United States
Licking Memorial Cancer Care Program at Licking Memorial Hospital
🇺🇸Newark, Ohio, United States
Community Hospital of Springfield and Clark County
🇺🇸Springfield, Ohio, United States
UVMC Cancer Care Center at Upper Valley Medical Center
🇺🇸Troy, Ohio, United States
Cleveland Clinic - Wooster
🇺🇸Wooster, Ohio, United States
Mount Carmel Cancer Services at Mount Carmel St. Ann's Hospital
🇺🇸Westerville, Ohio, United States
Genesis - Good Samaritan Hospital
🇺🇸Zanesville, Ohio, United States
Geisinger Medical Center
🇺🇸Danville, Pennsylvania, United States
Penn State Cancer Institute at Milton S. Hershey Medical Center
🇺🇸Hershey, Pennsylvania, United States
Hillman Cancer Center at University of Pittsburgh Cancer Institute
🇺🇸Pittsburg, Pennsylvania, United States
Pottstown Memorial Regional Cancer Center
🇺🇸Pottstown, Pennsylvania, United States
Mount Nittany Medical Center
🇺🇸State College, Pennsylvania, United States
CCOP - Syracuse Hematology-Oncology Associates of Central New York, P.C.
🇺🇸Syracuse, New York, United States
CCOP - Michigan Cancer Research Consortium
🇺🇸Ann Arbor, Michigan, United States
Comprehensive Cancer Center at Wake Forest University
🇺🇸Winston-Salem, North Carolina, United States
Strecker Cancer Center at Marietta Memorial Hospital
🇺🇸Marietta, Ohio, United States
Lipson Cancer and Blood Center at Rochester General Hospital
🇺🇸Rochester, New York, United States
Kimmel Cancer Center at Thomas Jefferson University - Philadelphia
🇺🇸Philadelphia, Pennsylvania, United States
Mercy Hospital
🇺🇸Coon Rapids, Minnesota, United States
Memorial Hospital
🇺🇸Carthage, Illinois, United States
Rose Ramer Cancer Clinic at Anderson Area Medical Center
🇺🇸Anderson, South Carolina, United States
William Beaumont Hospital - Royal Oak Campus
🇺🇸Royal Oak, Michigan, United States
Gibbs Regional Cancer Center at Spartanburg Regional Medical Center
🇺🇸Spartanburg, South Carolina, United States
CCOP - Kansas City
🇺🇸Kansas City, Missouri, United States
Roper St. Francis Healthcare - Roper Hospital
🇺🇸Charleston, South Carolina, United States
John Stoddard Cancer Center at Iowa Methodist Medical Center
🇺🇸Des Moines, Iowa, United States
Via Christi Cancer Center at Via Christi Regional Medical Center
🇺🇸Wichita, Kansas, United States
Northern Rockies Radiation Oncology Center
🇺🇸Billings, Montana, United States
Middletown Regional Hospital
🇺🇸Middletown, Ohio, United States
Rhode Island Hospital
🇺🇸Providence, Rhode Island, United States