comparision of melatonin and olanzapine in prevention and treatment of delirium in elderly male undergoing arthroplasty of hip or knee under neuraxial block
Not Applicable
- Conditions
- Health Condition 1: F05- Delirium due to known physiological conditionHealth Condition 2: O- Medical and Surgical
- Registration Number
- CTRI/2022/11/047545
- Lead Sponsor
- S NIJALINGAPPA MEDICAL COLLEGE AND HSK HOSPITA
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1Patients belonging to ASA I II III.
2Aged 60 years or more.
3 Patients undergoing hip or knee arthroplasty under neuraxial block.
Exclusion Criteria
1Dementia.
2Patient on Antipsychotic drugs.
3ASA 4.
4Patients with AMT (abbreviated mental test) score < 8.
5Patients receiving intra operative midazolam or pentazocine.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To compare the efficacy of oral melatonin, oral olanzapine and oral placebo(multivitamin) for prevention and treatment of post operative delirium in elderly patient after arthroplasty of hip or knee under neuraxial blockTimepoint: 7 days
- Secondary Outcome Measures
Name Time Method To estimate the proportion of post operative delirium and to notify the side effects of drugs used in postoperative delirium.Timepoint: 7 days