A comparative study between the efficacy of oral Cimetidine and low dose of systemic Meglumine Antimoniate (MA) with standard dose of systemic (MA) in the treatment of syrian cutaneous leishmaniasis patients.
Phase 3
- Conditions
- Cutaneous Leishmaniasis.Cutaneous leishmaniasis
- Registration Number
- IRCT2013123116016N1
- Lead Sponsor
- The University of Aleppo
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 90
Inclusion Criteria
parasitological confirmation; age between 5 to 65 years old; normal values of the liver, kidney, and pancreas function tests and EKG before treatment.
Exclusion criteria: contraindication to use (MA); pregnant and lactating women; patients with history of cardiac, renal and hepatic diseases; those under treatment with other drugs during the month prior to commencement of the study.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Diameter of lesion. Timepoint: Every two weeks from the beginning of the trial up to six weeks and then at 8 and 12 weeks. Method of measurement: Socal Method.
- Secondary Outcome Measures
Name Time Method Healing time for lesion. Timepoint: Every two weeks from the beginning of the trial up to six weeks and then at 8 and 12 weeks. Method of measurement: complete response, partial response and no response.